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  1. 15 de jul. de 2016 · Investigating epidemiology of metastatic colon and rectal cancer is challenging, because cancer registries seldom record metastatic sites. We used a population based approach to assess metastatic spread in colon and rectal cancers. 49,096 patients with colorectal cancer were identified from the nationwide Swedish Cancer Registry.

  2. 25 de out. de 2022 · Colorectal cancer (CRC) is the third most common cancer worldwide, with 1.1 million new cases per year, and is the second leading cause of cancer death.1 CRC occurs more frequently in middle- to high-income countries with an eightfold variation in incidence across the world. This rise may be associated with known risk factors, including alcohol intake, tobacco use, obesity, sedentariness and ...

  3. 17 de out. de 2022 · PURPOSE To develop recommendations for treatment of patients with metastatic colorectal cancer (mCRC). METHODS ASCO convened an Expert Panel to conduct a systematic review of relevant studies and develop recommendations for clinical practice. RESULTS Five systematic reviews and 10 randomized controlled trials met the systematic review inclusion criteria. RECOMMENDATIONS Doublet chemotherapy ...

  4. 25 de out. de 2022 · Key words: metastatic colorectal cancer, Clinical Practice Guidelines, diagnosis, treatment, follow-up INCIDENCE AND EPIDEMIOLOGY Colorectal cancer (CRC) is the third most common cancer worldwide, with 1.1 million new cases per year, and is the second leading cause of cancer death.1 CRC occurs more frequently in middle- to high-income countries ...

  5. 16 de fev. de 2021 · Colorectal cancer (CRC) is the third most common cause of cancer-related death in the United States, and in 2020, an estimated 147 950 new cases and 53 200 deaths were projected. 1 Among people diagnosed with colon cancer, 20% have metastatic CRC, 2 and 40% present with recurrence after previously treated localized disease. 3 The prognosis of metastatic CRC is poor, with a 5-year survival rate ...

    • Leah H Biller, Deborah Schrag
    • 2021
  6. •The 5-year relative OS for patients with metastatic colorectal cancer (mCRC) is ~15%.4 •Approximately 33% of patients with CRC will develop metastases either at presentation or follow-up.5 •Evaluating treatment options is complex due to the heterogeneity of the patient population, including different molecular subtypes.