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Metastatic CRC may consist of tumors identified at a distant site following a previously treated localized CRC (nonmetastatic or stage I-III) or may present de novo at stage IV, defined as metastatic disease or cancer that has spread outside the original colorectal mass.
- Leah H Biller, Deborah Schrag
- 2021
25 de out. de 2022 · This ESMO Clinical Practice Guideline provides key recommendations for managing metastatic colorectal cancer. •. It covers clinical and pathological diagnosis, staging and risk assessment, treatment and follow-up. •. Treatment algorithms for locoregional, advanced/metastatic and recurrent advanced colorectal cancer are provided. •.
17 de out. de 2022 · Treatment of Metastatic Colorectal Cancer: ASCO Guideline. Guideline Question. What is the recommended treatment for metastatic colorectal cancer (mCRC)? Target Population.
15 de jul. de 2016 · We investigated the patterns of metastasis from colon and rectal cancer to specific sites, depending on sex, age at diagnosis, histological subtype, stage, number of metastases, and whether the primary was situated in proximal or distal colon, or in the rectum.
- Matias Riihimäki, Matias Riihimäki, Akseli Hemminki, Jan Sundquist, Kari Hemminki, Kari Hemminki
- 10.1038/srep29765
- 2016
- Sci Rep. 2016; 6: 29765.
19 de set. de 2019 · Metastasis is the major cause of death in patients with colorectal carcinoma (CRC). The most common sites of metastasis are the liver and the peritoneum. Peritoneal carcinomatosis is often considered the end stage of the disease after the tumor has spread to the liver.
- E. Pretzsch, F. Bösch, J. Neumann, P. Ganschow, A. Bazhin, M. Guba, J. Werner, M. Angele
- 10.1155/2019/7407190
- 2019
- J Oncol. 2019; 2019: 7407190.
13 de fev. de 2023 · John Paul Shen. npj Precision Oncology 7, Article number: 16 ( 2023 ) Cite this article. 17k Accesses. 27 Citations. 63 Altmetric. Metrics. Abstract. Over the past two decades of successive...
16 de fev. de 2021 · Abstract. Importance: Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide with more than 1.85 million cases and 850 000 deaths annually. Of new colorectal cancer diagnoses, 20% of patients have metastatic disease at presentation and another 25% who present with localized disease will later develop metastases.
