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24 de abr. de 2020 · Lymphatic metastases are closely associated with tumor relapse and reduced survival in colorectal cancer (CRC). Here, the authors analysed the primary tumours, lymph node metastasis and...
- Chong Zhang, Lin Zhang, Tianlei Xu, Ruidong Xue, Liang Yu, Yuelu Zhu, Yunlong Wu, Qingqing Zhang, Do...
- 2020
28 de mai. de 2024 · Metastatic colorectal cancer ... The portal vein, which drains blood from the gastrointestinal tract, ... the spread of cancer to regional lymph nodes is associated with diminished DFS 15.
12 de mar. de 2021 · In this review, we focus on delineating the process of cancer cell migration to and through lymphatic vessels, survival in draining lymph nodes and further spread to other distant organs. In addition, emerging molecular targets and potential strategies to inhibit lymph node metastasis are discussed.
- Hengbo Zhou, Pin-Ji Lei, Timothy P Padera
- 10.3390/cells10030627
- 2021
- Cells. 2021 Mar; 10(3): 627.
12 de jun. de 2019 · Lymph node metastasis is regarded as an indubitable prognostic factor for predicting disease recurrence and survival in patients with colorectal cancer. Lymph node status based on examination of a resected specimen is a key element of the current staging system and is also a crucial factor to determine use of adjuvant chemotherapy ...
- Hye Jin Kim, Gyu–Seog Choi
- 2019
15 de jul. de 2016 · We investigated the patterns of metastasis from colon and rectal cancer to specific sites, depending on sex, age at diagnosis, histological subtype, stage, number of metastases, and whether...
- Matias Riihimäki, Matias Riihimäki, Akseli Hemminki, Jan Sundquist, Kari Hemminki, Kari Hemminki
- 2016
19 de set. de 2019 · Metastasis is the major cause of death in patients with colorectal carcinoma (CRC). The most common sites of metastasis are the liver and the peritoneum. Peritoneal carcinomatosis is often considered the end stage of the disease after the tumor has spread to the liver.
The invasion of lymphatic vessels by colorectal cancer (CRC) and its subsequent spread to draining lymph nodes is a key determinant of prognosis in this common and frequently fatal malignancy.
