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24 de abr. de 2020 · Nature Communications - Lymphatic metastases are closely associated with tumor relapse and reduced survival in colorectal cancer (CRC). Here, the authors analysed the primary tumours,...
- Chong Zhang, Lin Zhang, Tianlei Xu, Ruidong Xue, Liang Yu, Yuelu Zhu, Yunlong Wu, Qingqing Zhang, Do...
- 2020
12 de jun. de 2019 · Lymph node metastasis is regarded as an indubitable prognostic factor for predicting disease recurrence and survival in patients with colorectal cancer. Lymph node status based on examination of a resected specimen is a key element of the current staging system and is also a crucial factor to determine use of adjuvant chemotherapy ...
- Hye Jin Kim, Gyu–Seog Choi
- 2019
Há 4 dias · Metastatic colorectal cancer ... The portal vein, which drains blood from the gastrointestinal tract, ... the spread of cancer to regional lymph nodes is associated with diminished DFS 15.
12 de mar. de 2021 · In this review, we focus on delineating the process of cancer cell migration to and through lymphatic vessels, survival in draining lymph nodes and further spread to other distant organs. In addition, emerging molecular targets and potential strategies to inhibit lymph node metastasis are discussed.
- Hengbo Zhou, Pin-Ji Lei, Timothy P Padera
- 10.3390/cells10030627
- 2021
- Cells. 2021 Mar; 10(3): 627.
26 de abr. de 2024 · Liver metastases discovered at the timepoint of primary colorectal cancer diagnosis are classified as synchronous disease, and this includes patients with the incidental intraoperative finding of liver metastasis. Regarding metachronous liver metastasis there has been a change in nomenclature.
7 de dez. de 2021 · Vascular invasion is a common feature of colorectal cancer and its liver metastases. Intrahepatic portal venous invasion local to resected metastases occurs in approximately a quarter of cases (reported range 10-49%) and hepatic venous invasion in approximately one tenth of cases (reported range 5-24%) ( 10 ).
Metastasis of CRC remains a major problem after curative treatment and is the critical cause of CRC-related death.8The liver is the most common organ of distant metastasis in CRC.9Liver...
