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24 de abr. de 2020 · Nature Communications - Lymphatic metastases are closely associated with tumor relapse and reduced survival in colorectal cancer (CRC). Here, the authors analysed the primary tumours,...
- Chong Zhang, Lin Zhang, Tianlei Xu, Ruidong Xue, Liang Yu, Yuelu Zhu, Yunlong Wu, Qingqing Zhang, Do...
- 2020
12 de mar. de 2021 · In this review, we focus on delineating the process of cancer cell migration to and through lymphatic vessels, survival in draining lymph nodes and further spread to other distant organs. In addition, emerging molecular targets and potential strategies to inhibit lymph node metastasis are discussed.
- Hengbo Zhou, Pin-Ji Lei, Timothy P Padera
- 10.3390/cells10030627
- 2021
- Cells. 2021 Mar; 10(3): 627.
15 de jul. de 2016 · Colorectal cancer (CRC) is the third most common cancer worldwide 1. Approximately 56% of patients with CRC die from their cancer 2. Development of metastasis is a concern for patients and...
- Matias Riihimäki, Matias Riihimäki, Akseli Hemminki, Jan Sundquist, Kari Hemminki, Kari Hemminki
- 2016
19 de set. de 2019 · Invasion-metastasis cascade: local invasion of colorectal cancer cells into surrounding matrix (Step 1), intravasation into circulatory system (blood vessels/lymphatic vessels) (Step 2), systemic transportation (Step 3), extravasation (Step 4), colonization of distant organs (liver/peritoneum) (Step 5).
- E. Pretzsch, F. Bösch, J. Neumann, P. Ganschow, A. Bazhin, M. Guba, J. Werner, M. Angele
- 10.1155/2019/7407190
- 2019
- J Oncol. 2019; 2019: 7407190.
Lymphatic metastases are closely associated with tumor relapse and reduced survival in colorectalcancer(CRC).Howtumorcellsdisseminatewithinthelymphaticnetworkremains...
- Chong Zhang, Lin Zhang, Tianlei Xu, Ruidong Xue, Liang Yu, Yuelu Zhu, Yunlong Wu, Qingqing Zhang, Do...
- 2020
12 de nov. de 2021 · Kamila Naxerova utilizes genomic studies to describe the phylogenetic origins of lymphatic and distant metastasis in colorectal cancer. Laura Keller and Klaus Pantel address the metastatic process in relationship to cancer micrometastasis and dormancy.
The invasion of lymphatic vessels by colorectal cancer (CRC) and its subsequent spread to draining lymph nodes is a key determinant of prognosis in this common and frequently fatal malignancy.
