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22 de jun. de 2022 · Recent changes in guidelines recommend beginning screening for colon cancer at the age of 45. Circulating tumor DNA presents an opportunity to select patients for administration of adjuvant chemotherapy. Immunotherapy is an option for patients with a deficiency in mismatch repair proteins. However, its efficacy outside of this group of patients ...
4 de ago. de 2022 · Molecular characterization of colorectal cancer related peritoneal metastatic disease | Nature Communications. Article. Open access. Published: 04 August 2022. Molecular...
19 de abr. de 2022 · View article impact. Share on. ORIGINAL RESEARCH article. Front. Oncol., 19 April 2022. Sec. Gastrointestinal Cancers: Colorectal Cancer. Volume 12 - 2022 | https://doi.org/10.3389/fonc.2022.813253. Comprehensive Molecular Profiling of Colorectal Cancer With Situs Inversus Totalis by Next-Generation Sequencing.
Coloncancer(CC)isthethirdleadingcauseofcancer-related death inadultpatientsintheUS.Anestimated106,180newCC cases and 52,580 deathsareexpected in2022. Althoughnew 1. 2 , treatments have 3 improved outcomes, thefiveyearrelativesurvival remains pooratonly64.7%. 2 Theoddsareworseforpatientswith.
29 de mar. de 2022 · Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies. Cancers 2022, 14, 1732.https:// doi.org/10.3390/cancers14071732 Academic Editors: Luis Bujanda, Ajay Goel and Ane Etxart Received: 14 March 2022 Accepted: 27 March 2022 Published: 29 March 2022
19 de jan. de 2022 · Background: Molecular characterisation of colorectal cancer (CRC) has demonstrated the regulatory role of epigenetic alterations, such as DNA methylation, in CRC tumorigenesis (1). Robust molecular profiling of CRC has the potential to provide critical diagnostic and prognostic information.
30 de jun. de 2022 · Article. Open access. Published: 30 June 2022. Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of...
