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25 de ago. de 2018 · Entrapment efficiency (EE) is a crucial parameter for the evaluation of nanocarriers. The accurate measurement of EE demands clear separation of nanocarriers from free drugs, which so far has not been clearly validated due to a lack of functional tools to identify nanocarriers.
- Yongjiu Lv, Haisheng He, Jianping Qi, Yi Lu, Weili Zhao, Xiaochun Dong, Wei Wu
- 2018
2 de dez. de 2021 · The aim of the present study was to formulate clindamycin (CLN) as a microsponge based gel to release the drug in a controlled manner and reduce the side effects in the treatment of acne.
- Alaa Khattab, Abdulhakim Nattouf
- 2021
18 de fev. de 2020 · Entrapment efficiency (Ee) defines the ratio between the weight of entrapped drug and the total weight of drug added to the dispersion. The amount of drug encapsulated per unit weight of the NLC is determined by ultrafiltration-centrifugation method.
- Iti Chauhan, Mohd Yasir, Madhu Verma, Alok Pratap Singh
- 10.34172/apb.2020.021
- 2020
- Adv Pharm Bull. 2020 Jun; 10(2): 150-165.
2 de dez. de 2021 · The aim of this study was to develop a sustained release microsponge based gel of CLN-HCl as a model for a highly water-soluble drug with high entrapment efficiency of the drug inside microsponges and acceptable other physicochemical properties. Initially, CLN-HCl was converted to CLN-free base.
- ALAA KHATTAB, Abdulhakim Nattouf
- Sci Rep. 2021; 11: 23345.
- 10.1038/s41598-021-02826-7
- 2021
1 de out. de 2023 · Entrapment efficiency is a critical parameter that ensures proper entrapment of drugs in nanosystems. Multiple assessments are required to ensure drug retention in developed nanocarriers. CatBoost was the model of choice for predicting entrapment efficiency.
28 de mai. de 2020 · Introduction. Nanostructured lipid carrier (NLC) is the enhanced version of solid-lipid nanoparticle (SLN), a type of lipid-based drug delivery system.
21 de abr. de 2009 · The entrapment efficiency (EE) and release in vitro are very important physicochemical characteristics of puerarin submicron emulsion (SME). In this paper, the performance of ultrafiltration (UF), ultracentrifugation (UC), and microdialysis (MD) for determining the EE of SME were evaluated, respectively.
