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  1. Há 4 horas · 4. Transfer by pipetting the MC-38 cells from the cryovial into a 15 mL falcon tube filled with 10 mL of complete media. Centrifuge at 400× g for 5 min. Aspirate the supernatant, resuspend cell pellet in 1 mL of complete media and transfer 0.5 mL to each of the T175 cm 2 culture flasks filled with 25 mL complete media.

  2. Há 4 horas · Abstract. Pancreatic cancer is associated with a high mortality rate, and there are still very few effective treatment options. Patient-derived xenografts have proven to be invaluable preclinical disease models to study cancer biology and facilitate testing of novel therapeutics. However, the severely immune-deficient mice used to generate ...

  3. Há 4 horas · Gock M, Kühn F, Mullins CS et al (2016) Tumor take rate optimization for colorectal carcinoma patient-derived xenograft models. Biomed Res Int 2016:1715053. Article PubMed PubMed Central Google Scholar

  4. Há 4 horas · Loukopoulos P, Kanetaka K, Takamura M et al (2004) Orthotopic transplantation models of pancreatic adenocarcinoma derived from cell lines and primary tumors and displaying varying metastatic activity. Pancreas 29(3):193–203. Article CAS PubMed Google Scholar

  5. Há 1 dia · 127P RAS, RAF and NF1 oncogenic mutations in KRAS-mutated lung adenocarcinoma; KRAS amplification and mutation are independent events in gastroesophageal adenocarcinomas (GEA). KRAS amplification and mutation as independent events in gastroesophageal adenocarcinomas (GEA). Molecular profile of KRAS G12C-mutant colorectal and non-small-cell lung ...

  6. Há 1 dia · Establishment of a human lung adenocarcinoma A549 cell line with RNA interference for Y-box binding ... P2-051: Cathepsin D, B and L are down-regulated in fibroblasts from Alzheimer's disease patients; Hypothesis Article: Food Proteins are a Potential Resource for Mining Cathepsin L Inhibitory Drugs t...