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  1. Há 11 horas · Isabella I ( Spanish: Isabel I; 22 April 1451 – 26 November 1504), [2] also called Isabella the Catholic (Spanish: Isabel la Católica ), was Queen of Castile and León from 1474 until her death in 1504. She was also Queen of Aragon from 1479 until her death as the wife of King Ferdinand II. Reigning together over a dynastically unified Spain ...

  2. Há 11 horas · Philip's first wife was his double first cousin, Maria Manuela, Princess of Portugal. She was a daughter of Philip's maternal uncle, John III of Portugal, and paternal aunt, Catherine of Austria. They were married at Salamanca on 12 November 1543. The marriage produced one son in 1545, after which Maria died four days later due to haemorrhage: