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January–June

1. January 19 – King Christian II of Denmark and Norway defeats the Swedes, at Lake Åsunden in Sweden. The Swedish regent Sten Sture the Younger is mortally wounded in the battle. He is rushed towards Stockholm, in order to lead the fight against the Danes from there, but dies from his wounds on February 3. 2. April 16 – Revolt of the Comuneros: Citizens of Toledo, Castile opposed to the rule of the Flemish-born Charles V, Holy Roman Emperor, rise up when the royal government attempts to unse...

July–December

1. July 1 – La Noche Triste (Night of Sorrow): The forces of Cuitláhuac, Aztec ruler of Tenochtitlan, gain a major victory against the forces of conquistador Hernán Cortés. This results in the death of about 400 conquistadors, and some 2,000 of their Native Americanallies. However, Cortés and the most skilled of his men manage to escape and later regroup. 2. July 7 – Otumba near Lake Texcaco: The Spaniards defeat the Aztecs. 1. August – Martin Luther publishes To the Christian Nobility of the...

Date unknown

1. The Franciscan friar Matteo Bassi is inspired to return to the primitive life of solitude and penance, as practiced by St. Francis, giving rise to the Order of Friars Minor Capuchin. 2. Duarte Barbosa returns to Cananor. 3. Aleksandra Lisowska (Roxelana) is given as a gift to Suleiman Ion the occasion of his accession to the throne. 4. King Manuel I creates the public mail service of Portugal, the Correio Público.