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Mycobacterium africanum é uma espécie do gênero Mycobacterium, com maior incidência em países da África Ocidental. Os sintomas causados por sua infecção assemelham-se aos de M. tuberculosis. Ele é um membro do complexo Mycobacterium tuberculosis. [1]
Mycobacterium africanum is a species of bacteria that causes tuberculosis in West Africa. It is a member of the Mycobacterium tuberculosis complex, but has some genetic and phenotypic differences that affect its pathogenicity and treatment.
28 de set. de 2010 · Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis.
- Bouke C. de Jong, Martin Antonio, Sebastien Gagneux, Sebastien Gagneux
- 2010
26 de mai. de 2022 · Tuberculosis (TB), one of the deadliest threats to human health, is mainly caused by 2 highly related and human-adapted bacteria broadly known as Mycobacterium tuberculosis and Mycobacterium africanum.
In this chapter, we summarize the geographical distribution of the M. africanum lineages within the region, describe biological and clinical differences and the consequent implications for TB control in West Africa.
- Dorothy Yeboah-Manu, Bouke C. de Jong, Florian Gehre
- 2017
Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex (MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis sensu stricto, as well as two lineages (L5 and L6) traditionally referred to as Mycobacterium africanum.
Phylogenomic analysis of the species of the Mycobacterium tuberculosis complex demonstrates that Mycobacterium africanum, Mycobacterium bovis, Mycobacterium caprae, Mycobacterium microti and Mycobacterium pinnipedii are later heterotypic synonyms of Mycobacterium tuberculosis.
