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  1. Smallpox. Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. It was one of the most devastating diseases known to humanity and caused millions of deaths before it was eradicated. It is believed to have existed for at least 3000 years. The smallpox vaccine, created by Edward Jenner in 1796 ...

  2. Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. It was one of the most devastating diseases known to humanity and caused millions of deaths before it was eradicated. It is believed to have existed for at least 3000 years. The smallpox vaccine, created by Edward Jenner in 1796, was the ...

  3. 28 de jun. de 2016 · What is smallpox? Smallpox is an ancient disease caused by the variola virus. Early symptoms include high fever and fatigue. The virus then produces a characteristic rash, particularly on the face, arms and legs. The resulting spots become filled with clear fluid and later, pus, and then form a crust, which eventually dries up and falls off.

  4. 30 de mai. de 2024 · The World Health Organization (WHO) Advisory Committee on variola virus Research (ACVVR), held its twenty-fifth meeting on 25-26 October 2023. The recommendations of the Committee are summarized in this report.

  5. 8 de dez. de 2020 · Como podem as vacinas ajudar. As vacinas contêm partes enfraquecidas ou inativadas de um determinado organismo (antigénio) que desencadeia uma resposta imunitária do corpo. As vacinas mais recentes contêm a matriz para produzir antigénios e não o próprio antigénio. Independentemente de uma vacina ser constituída pelo próprio ...

  6. 21 de set. de 2023 · The World Health Organization (WHO) Advisory Committee on variola virus Research (ACVVR), held its twenty-fourth meeting on 29-30 November 2022 at WHO Headquarters in Geneva. The recommendations of the Committee are summarized in this report.

  7. 21 de jun. de 2016 · Smallpox has two main forms: variola major and variola minor. The two forms showed similar lesions. The disease followed a milder course in variola minor, which had a case fatality rate of less than 1 per cent. The fatality rate of variola major was around 30%. There are two rare forms of smallpox: haemorrhagic and malignant.

  8. 26 de ago. de 2024 · Key facts. Mpox, previously known as monkeypox, is a viral illness caused by the monkeypox virus, a species of the genus Orthopoxvirus. There are two distinct clades of the virus: clade I (with subclades Ia and Ib) and clade II (with subclades IIa and IIb). In 2022–2023 a global outbreak of mpox was caused by the clade IIb strain.

  9. Research using live variola virus. The period since eradication has been defined by a lengthy, complex and unresolved debate focused on the destruction of the last remaining stocks of live variola virus. This global variola virus stock, consisting of isolates of both variola major and the milder form, variola minor, was restricted to 2 ...

  10. Advisory Committee for Variola virus Research. The Advisory Committee for Variola virus Research (ACVVR) was convened in 1999 to implement WHA Resolution (WHA52). The ACVVR is composed of members from all WHO regions and advised by scientific academic experts from areas such as public health, fundamental applied research and regulatory agencies.

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