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  1. www.bmj.com › content › 376Alternative to prophylactic antibiotics for the treatment of ...

    9 de mar. de 2022 · The study showed a small numerical difference in UTI incidence between the daily antibiotics and methenamine hippurate groups, but the potential trade-off includes the avoidance of antibiotic consumption, which is closely associated with antimicrobial resistance development.

  2. www.ncbi.nlm.nih.gov › pmc › articlesEvaluation of methenamine for urinary tract infection ...

    23 de set. de 2019 · Methenamine hippurate is dosed 1 g twice daily for prophylaxis, whereas methenamine mandelate is dosed 1 g four times daily. The clinical trials that brought both forms of methenamine to market included an insufficient number of patients age ⩾ 65 to assess response differences in this population, and the manufacturer recommends methenamine ...

    • Amy Chwa, Kevin Kavanagh, Sunny Anne Linnebur, Danielle R. Fixen
    • 10.1177/2042098619876749
    • 2019
    • 2019

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  4. www.ncbi.nlm.nih.gov › pmc › articlesSafety and Efficacy of Methenamine Hippurate for the ...

    We found that methenamine is well tolerated and is useful in reducing UTI, antibiotic prescriptions, and hospitalization in RTR with recurrent UTI. Larger prospective studies are needed to confirm these findings. Keywords: Urinary Tract Infection, Methenamine, Renal Transplant. Go to: BACKGROUND.

    • Ian Hollyer, Francesca Varias, Bing Ho, Michael G Ison
    • 2019

  5. pubmed.ncbi.nlm.nih.gov › 35535708Methenamine hippurate compared with antibiotic prophylaxis to ...

    Objective: To assess the clinical effectiveness and cost-effectiveness of methenamine hippurate (Hiprex ®; Mylan NV, Canonsburg, PA, USA) compared with current standard care (antibiotic prophylaxis) for recurrent urinary tract infection prevention in adult women.

  6. www.ncbi.nlm.nih.gov › pmc › articlesMethenamine hippurate for preventing urinary tract infections

    17 de out. de 2012 · It is uncertain whether methenamine hippurate* and methenamine mandelate** are equivalent in effectiveness (Gow 1974; Greenwood 1981; Kasanen 1974). The mandelate salt is not widely available. This review will only consider the effectiveness of methenamine hippurate in preventing UTIs.

    • Bon San B Lee, Tushar Bhuta, Judy M Simpson, Jonathan C Craig
    • 10.1002/14651858.CD003265.pub3
    • 2012
    • 2012/10

  7. evidence.nihr.ac.uk › alert › methenamine-as-good-asMethenamine is as good as antibiotics at preventing UTIs

    20 de dez. de 2022 · Many patients tell us they benefit from taking methenamine hippurate (Hiprex). Others report that their doctors are reluctant or refuse to prescribe it. We therefore hope this study, and subsequent review of the guidelines, will allow more patients to access and benefit from this treatment.

  8. www.goodrx.com › methenamine-hippurate › what-isMethenamine Hippurate (Hiprex) and Methenamine Mandelate ...

    7 de set. de 2021 · Methenamine hippurate (Hiprex) is an antibiotic medication used to prevent and control urinary tract infections (UTIs). It's meant for people who need long-term prevention, not to treat active infections. Methenamine hippurate (Hiprex) is taken by mouth twice daily.