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O osteossarcoma é a neoplasia maligna primária óssea não hematológica mais comum nas crianças e adolescentes. Dor e edema são os sintomas manifestos mais comuns. Embora possa ocorrer em qualquer idade, a doença geralmente afeta pacientes na segunda e na terceira década de vida, atingindo a intensidade máxima entre 13 e 16 anos de ...
15 de dez. de 2023 · Summary. Osteosarcoma is the most common non-haematological primary malignant neoplasm of bone in children and adolescents. Pain and swelling are the most common presenting symptoms. Although it can occur at any age, it usually affects patients in the second and third decade of life with a peak incidence between 13 and 16 years of age.
Definição. O sarcoma de Kaposi (SK) é uma neoplasia linfovascular de baixo grau associada à infecção por herpes-vírus humano tipo 8 (HHV-8, também conhecido como herpes-vírus do sarcoma de Kaposi [HVSK]). [1] As lesões costumam envolver locais mucocutâneos, mas podem se estender e acabar envolvendo linfonodos e órgãos viscerais.
14 de jan. de 2021 · Patients frequently complain of diffuse bony pain with a history of limited sunlight exposure. Proximal muscle weakness, spinal tenderness to percussion, pseudofractures, and skeletal deformities are found commonly. Diagnosis is made via laboratory results with a low vitamin D level in the setting of low or normal calcium and an elevated intact ...
1 de set. de 2022 · Paget’s disease of bone (PDB) is a chronic localised bone remodelling disorder characterised by increased bone resorption, bone formation, and remodelling, which may lead to major long-bone and skull deformities. Majority of patients are asymptomatic. Symptomatic patients typically experience pain localised to the bone or joint, either from ...
10 de mar. de 2023 · Patellofemoral pain syndrome is one of the most common disorders of the knee, accounting for 25% of knee injuries seen in a sports medicine clinic. The causes of patellofemoral problems are multifactorial, including abnormal patellofemoral joint mechanics, lower kinetic chain alterations, and overuse. Patients typically note the insidious onset ...
A patologia deve ser analisada por um patologista que tenha experiência em histologia de sarcoma. Métodos laboratoriais de diagnóstico podem incluir imuno-histoquímica, citogenética e teste genético molecular. O tratamento se baseia no estádio e no subtipo histológico, com apenas alguns subtipos sendo sensíveis à quimioterapia.
12 de mar. de 2024 · Osteochondritis dissecans is an idiopathic lesion of subchondral bone. Majority of patients are adolescent or young adult athletes. Main joints involved include the knee, ankle, and radiocapitellar joint of the elbow. Bilateral in up to 25%. Variable presentation: traumatic or atraumatic, insidious onset, non-specific joint pain, exacerbation ...
3 de mai. de 2024 · Summary. Tumour lysis syndrome (TLS) is an oncological emergency caused by rapid breakdown of cancer cells and subsequent release of large amounts of intracellular content into the bloodstream. The pathophysiological manifestations of TLS can lead to acute kidney injury, cardiac arrhythmias, seizures, and neuromuscular dysfunction, which can ...
11 de mai. de 2023 · Actinomycosis is a rare, pyogenic, granulomatous, subacute to chronic infection caused by actinomycetes. Actinomycetes are a group of anaerobic gram-positive bacteria with high guanine-cytosine content found as natural flora of the oral cavity. The most frequent features are ulcer and granuloma formation, and the presence of multiple abscesses ...
