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  1. 28 de mai. de 2024 · Metastatic colorectal cancer ... The portal vein, which drains blood from the gastrointestinal tract, ... the spread of cancer to regional lymph nodes is associated with diminished DFS 15.

  2. 12 de jun. de 2019 · Lymph node metastasis is regarded as an indubitable prognostic factor for predicting disease recurrence and survival in patients with colorectal cancer. Lymph node status based on examination of a resected specimen is a key element of the current staging system and is also a crucial factor to determine use of adjuvant chemotherapy ...

    • Hye Jin Kim, Gyu–Seog Choi
    • 2019
  3. 12 de mar. de 2021 · Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate. Thus, it is important to understand the mechanisms by which lymph node metastases progress and how they can be targeted to provide therapeutic benefits.

    • Hengbo Zhou, Pin-Ji Lei, Timothy P Padera
    • 10.3390/cells10030627
    • 2021
    • Cells. 2021 Mar; 10(3): 627.
  4. 19 de set. de 2019 · Metastasis is the major cause of death in patients with colorectal carcinoma (CRC). The most common sites of metastasis are the liver and the peritoneum. Peritoneal carcinomatosis is often considered the end stage of the disease after the tumor has spread to the liver.

    • E. Pretzsch, F. Bösch, J. Neumann, P. Ganschow, A. Bazhin, M. Guba, J. Werner, M. Angele
    • 10.1155/2019/7407190
    • 2019
    • J Oncol. 2019; 2019: 7407190.
  5. 15 de jul. de 2016 · In colorectal cancer patients with solitary metastases the survival differed between 5 and 19 months depending on T or N stage. Metastatic patterns differ notably between colon and rectal...

  6. The invasion of lymphatic vessels by colorectal cancer (CRC) and its subsequent spread to draining lymph nodes is a key determinant of prognosis in this common and frequently fatal malignancy.