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  1. 15 de jul. de 2016 · Of all patients with metastatic cancer, the most common sites of metastasis were the liver (70% in colon cancer/70% in rectal cancer) and the thorax (32%/47%). In colon cancer, the third most common site was the peritoneum (21%) whereas in rectal cancer it was the bone (12%).

    • Matias Riihimäki, Matias Riihimäki, Akseli Hemminki, Jan Sundquist, Kari Hemminki, Kari Hemminki
    • 10.1038/srep29765
    • 2016
    • Sci Rep. 2016; 6: 29765.
  2. 25 de out. de 2022 · Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomised trials.

  3. 17 de out. de 2022 · PDF. Abstract. Purpose. To develop recommendations for treatment of patients with metastatic colorectal cancer (mCRC). Methods. ASCO convened an Expert Panel to conduct a systematic review of relevant studies and develop recommendations for clinical practice. Results.

  4. Há 4 dias · Despite extensive research and improvements in understanding colorectal cancer (CRC), its metastatic form continues to pose a substantial challenge, primarily owing to limited therapeutic options ...

  5. Há 2 dias · Colorectal cancer (CRC) ranks third in incidence and second in mortality among cancer globally . The main cause of death in CRC patients is metastasis, with the liver being the most frequently metastatic site. Approximately 20% of CRC patients are diagnosed with metastatic CRC and show a poor prognosis with 5-year survival lower than 20% .

  6. 25 de out. de 2022 · Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up5 A. Cervantes1,2, R. Adam3, S. Roselló1,2, D. Arnold4, N. Normanno5, J. Taïeb6,7, J. Seligmann8, T. De Baere9,10,11, P. Osterlund12,13, T. Yoshino14 & E. Martinelli15, on behalf of the ESMO Guidelines Committee*

  7. Metastatic CRC may consist of tumors identified at a distant site following a previously treated localized CRC (nonmetastatic or stage I-III) or may present de novo at stage IV, defined as metastatic disease or cancer that has spread outside the original colorectal mass.