Resultado da Busca
3 de mar. de 2014 · In 2001, three groups independently identified a new mechanism of tumor metastasis, namely the induction of tumor lymphangiogenesis, by combining the use of the new lymphatic marker LYVE1 with overexpression of VEGF-C or VEGF-D in experimental tumor models ( 6 – 8 ). In these studies, overexpression of VEGF-C or VEGF-D promoted the growth of ...
15 de jul. de 2016 · Thoracic metastases are almost as common as liver metastases in rectal cancer patients with a low stage at diagnosis. In colorectal cancer patients with solitary metastases the survival differed between 5 and 19 months depending on T or N stage. Metastatic patterns differ notably between colon and rectal cancers.
7 de nov. de 2015 · Colorectal cancer (CRC) is a common malignancy worldwide. In CRC patients, metastases are the main cause of cancer-related mortality. In a group of metastatic CRC patients, the metastases are limited to a single site (solitary organ); the liver and lungs are the most commonly involved sites. When metastatic disease is limited to the liver and ...
12 de nov. de 2021 · Cancer metastasis is the process by which primary cancer cells invade through the lymphatic or blood vessels to distant sites. The molecular mechanisms by which cancer cells spread either through the lymphatic versus blood vessels or both are not well established. Two major developments have helped us to understand the process more clearly. First, the development of the sentinel lymph node ...
13 de jul. de 2015 · Breast cancer remains the leading cause of cancer mortality worldwide, despite a significant decline in death rates due to early detection. The majority of cancer mortalities are due to the metastasis of tumor cells to other organs. Metastasis or tumor cell dissemination occurs via the hematogenous and lymphatic systems.
12 de mar. de 2020 · Metastasis is the hallmark of cancer that is responsible ... In colorectal cancer, ... excess LMW‐HA in the tumor microenvironment facilitates lymphatic metastasis via disruption of ...
21 de jul. de 2019 · Colorectal cancer (CRC) is one of the most common cancers in the world. About two third of patients with CRC will develop distant recurrence at some point in time. Liver is the most common site where distant metastasis takes place. While the overall survival (OS) of patients with metastatic CRC was poor about 3 decades ago, there has been ...
