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  1. Há 2 dias · Metastatic colorectal cancer ... The portal vein, which drains blood from the gastrointestinal tract, ... the spread of cancer to regional lymph nodes is associated with diminished DFS 15.

  2. 24 de abr. de 2020 · Nature Communications - Lymphatic metastases are closely associated with tumor relapse and reduced survival in colorectal cancer (CRC). Here, the authors analysed the primary tumours,...

    • Chong Zhang, Lin Zhang, Tianlei Xu, Ruidong Xue, Liang Yu, Yuelu Zhu, Yunlong Wu, Qingqing Zhang, Do...
    • 2020
  3. 12 de mar. de 2021 · In this review, we focus on delineating the process of cancer cell migration to and through lymphatic vessels, survival in draining lymph nodes and further spread to other distant organs. In addition, emerging molecular targets and potential strategies to inhibit lymph node metastasis are discussed.

    • Hengbo Zhou, Pin-Ji Lei, Timothy P Padera
    • 10.3390/cells10030627
    • 2021
    • Cells. 2021 Mar; 10(3): 627.
  4. 19 de set. de 2019 · Invasion-metastasis cascade: local invasion of colorectal cancer cells into surrounding matrix (Step 1), intravasation into circulatory system (blood vessels/lymphatic vessels) (Step 2), systemic transportation (Step 3), extravasation (Step 4), colonization of distant organs (liver/peritoneum) (Step 5).

    • E. Pretzsch, F. Bösch, J. Neumann, P. Ganschow, A. Bazhin, M. Guba, J. Werner, M. Angele
    • 10.1155/2019/7407190
    • 2019
    • J Oncol. 2019; 2019: 7407190.
  5. 15 de jul. de 2016 · Colorectal cancer (CRC) is the third most common cancer worldwide 1. Approximately 56% of patients with CRC die from their cancer 2. Development of metastasis is a concern for patients and...

    • Matias Riihimäki, Matias Riihimäki, Akseli Hemminki, Jan Sundquist, Kari Hemminki, Kari Hemminki
    • 2016
  6. 1 de nov. de 2023 · Metastasis is a major cause of cancer-related death in CRC. The treatment of metastatic CRC has progressed minimally. However, the potential molecular mechanisms involved in CRC metastasis have remained to be comprehensively clarified.

  7. The invasion of lymphatic vessels by colorectal cancer (CRC) and its subsequent spread to draining lymph nodes is a key determinant of prognosis in this common and frequently fatal malignancy.