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  1. 14 de jul. de 2022 · Wnt signaling is a highly conserved signaling pathway that plays a key role in controlling embryo and organ development and cancer progression. Whole genome sequencing and gene expression profiling analysis show that Wnt signal is mainly involved in the process of cancer proliferation and metastasis.

  2. 22 de jun. de 2022 · Recent changes in guidelines recommend beginning screening for colon cancer at the age of 45. Circulating tumor DNA presents an opportunity to select patients for administration of adjuvant chemotherapy. Immunotherapy is an option for patients with a deficiency in mismatch repair proteins.

  3. 4 de ago. de 2022 · A significant proportion of colorectal cancer (CRC) patients develop peritoneal metastases (PM) in the course of their disease.

  4. Introduction. Colorectal cancer (CRC) is the third diagnosed malignant tumor worldwide, accounting for approximately 9% of annual cancer death ( 1 ). More than 90% of CRCs are adenocarcinoma, resulting from normal glandular colonic and rectum epithelium.

  5. changes in guidelines recommend beginning screening for colon cancer at the age of 45. Circulating tumor DNA presents an opportunity to select patients for administration of adjuvant chemotherapy.

  6. 24 de mai. de 2023 · The heterogeneity of CRC tumors plays a critical role in the development of treatment resistance, which underscores the need to understand the molecular mechanism involved in CRC to develop novel targeted therapeutic strategies.

  7. 29 de mar. de 2022 · This study recommends that culinary herbs and spices help to prevent and treat CRC by inhibiting the growth of human colorectal cancer cells via molecular signaling pathways.