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  1. The Seto lab is devoted to working towards obtaining a complete understanding of the functions, mechanisms of action, and regulation of HDACs, which play pivotal roles in the regulation of gene expression and are indispensable in numerous biological processes.

  2. Dr. Seto held the Ralph R. Kaul Endowed Professorship at the Moffitt Cancer Center and was the chair of the Molecular Oncology Department before moving to George Washington University. Early in his career, Dr. Setoʼs laboratory discovered and cloned two histone deacetylase enzymes, HDAC2 and HDAC3.

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    B.S., University of California, Irvine, 1981
    Ph.D., University of California, San Francisco, 1990

    Dr. Seto’s laboratory focuses on understanding histone deacetylase, an enzyme that epigenetically regulates how certain genes turn on or off. As the associate center director, Dr. Seto is also developing three basic science research programs that will help the center’s bid for National Cancer Institute designation: cancer biology, immunology/immuno...

    The Seto lab is devoted to obtaining a complete understanding of the functions, mechanisms of action, and regulation of histone deacteylases (HDACs), an enzyme that catalyze the removal of acetyl groups from the lysine residues of histones. These enzymes play a pivotal role in the regulation of gene transcription and are indispensable in numerous e...

    NIH R01 CA240529 Regulation of anti-tumor immunity by HDAC11 06/01/2020 – 05/31/2025 NIH T32 CA247756 Cancer Biology Training Program (CBTP) 07/01/2020 – 06/30/2025 NIH R01 AI153110 Design and development of HDAC11-specific chemical inhibitors for disease treatments 03/01/2021 – 02/28/2026

    BMSC 8210 Genes to Cells CANC 8221 The Basic Science of Oncology CANC 8222 Molecular Oncology and Cancer Epigenetics BIOC 6222 Biochemical Genetics and Medicine BIOC 6230 New Technologies in Scientific Research

    This faculty member (or a member of their immediate family) has reported a financial interest with the health care related companies listed below. These relations have been reported to the University and, when appropriate, management plans are in place to address potential conflicts. 1. None

  3. Seto's rapid prototyping lab fosters interdisciplinary collaboration to create new technologies to improve public health. Before coming to the University of Washington, he was Associate Professor of Environmental Health Sciences at UC Berkeley.

  4. Contact. Ed Seto, PhD. Associate Center Director for Basic Science in GWCC. Department of Biochemistry and Molecular Medicine. The George Washington University. Science and Engineering Building, Suite 8800. 800 22 nd Street, NW. Washington, DC 20052. Email: seto@gwu.edu.

  5. Betselot Zelalem, BSHS ’20, chose to enroll in the Medical Laboratory Sciences Program at GW because it combined her interest in the molecular level of science and medicine. Read More “The MSHS program in clinical microbiology helped me advance to new career opportunities and increase my salary,” said Zara Tariq.

  6. Welcome to the HIVE Lab. The HIVE Lab group is involved in developing the High-performance Integrated Virtual Environment (HIVE) which is a collaborative project between HIVE group at the CBER Food and Drug Administration ( FDA) and Dr. Raja Mazumder's HIVE Lab team at George Washington University ( GW ).