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  1. 9 de jul. de 2021 · Review Article. Published: 09 July 2021. Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation. Ernesto S. Nakayasu, Marina...

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      Full Size Table - Tutorial: best practices and...

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      Metrics - Tutorial: best practices and considerations for...

  2. 8 de dez. de 2022 · For quantitative assays, quality control samples should be at concentrations either throughout the analytical measurement range of the assay or at important medical decision limits, with a...

  3. 8 de jul. de 2021 · Abstract. Mass spectrometry-based metabolomics approaches can enable detection and quantification of many thousands of metabolite features simultaneously. However, compound identification...

    • Saleh Alseekh, Asaph Aharoni, Yariv Brotman, Kevin Contrepois, John D'Auria, Jan Ewald, Jennifer C. ...
    • 2021
  4. Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies. Metabolomics. 2018;14 (6):72. doi: 10.1007/s11306-018-1367-3. Epub 2018 May 18.

    • David Broadhurst, Royston Goodacre, Stacey N. Reinke, Stacey N. Reinke, Julia Kuligowski, Ian D. Wil...
    • 2018
  5. Furthermore, we describe how specialized quality control samples of varying sample complexity can be incorporated into the experimental workflow and how they can be used to rigorously assess detailed aspects of the instrument performance.

    • Wout Bittremieux, David L. Tabb, Francis Impens, An Staes, Evy Timmerman, Lennart Martens, Kris Lauk...
    • 2018
  6. 1 de jan. de 2017 · Validation, quality control, and compliance practice for mass spectrometry assays in the clinical laboratory - ScienceDirect. Mass Spectrometry for the Clinical Laboratory. 2017, Pages 63-76. Chapter 4 - Validation, quality control, and compliance practice for mass spectrometry assays in the clinical laboratory. Author links open overlay panel.

  7. 7 de set. de 2017 · Therefore, a comprehensive and systematic approach to quality control is an essential requirement to inspire confidence in the generated results. A typical mass spectrometry experiment consists of multiple different phases including the sample preparation, liquid chromatography, mass spectrometry, and bioinformatics stages.