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  1. Physical activity/exercise is considered one of the main strategies to counteract frailty-related physical impairment in the elderly. Exercise reduces age-related oxidative damage and chronic inflammation, increases autophagy, and improves mitochondrial function, myokine profile, insulin-like growth factor-1 (IGF-1) signaling pathway, and ...

    • Javier Angulo, Mariam El Assar, Alejandro Álvarez-Bustos, Leocadio Rodríguez-Mañas
    • 2020
  2. Physical activity and exercise: Strategies to manage frailty. Javier Angulo, Mariam El Assar, Alejandro Álvarez Bustos, Leocadio Rodríguez-Mañas. PII: DOI: Reference:...

  3. 1 de mar. de 2020 · Physical activity and exercise: Strategies to manage frailty. March 2020. Redox Biology 35 (3):101513. DOI: 10.1016/j.redox.2020.101513. License. CC BY-NC-ND. Authors: Javier...

  4. TLDR. An intervention that includes proper nutrition and exercise training may be essential for the prevention of frailty, as assessed using a broad sense frailty scale, the Clinical Frailty Scale (CSF), suggesting that reverse metabolism due to malnutrition in elderly type 2 DM patients might be involved. Expand.

  5. 28 de mar. de 2023 · There are two main intervention goals for an exercise/physical activity program for the prevention of fragility fractures. The first of these is to target bone; a 2% increase in hip and spine BMD has been associated with a 15–22% and 28% reduction in the risk of hip and vertebral fractures, respectively .

    • Elsa Dent
  6. 19 de jan. de 2021 · Given the multidimensional nature of frailty comprising of physical, cognitive and social domains, reversing, preventing or slowing down progression of frailty requires a targeted multicomponent approach including physical exercise, management of polypharmacy, falls, nutrition, loneliness, cognitive impairment and depression for ...

  7. 28 de mar. de 2023 · Current evidence-based clinical practice guidelines for frailty, osteoporosis, and fracture prevention recommend a multifaceted and targeted approach to optimise muscle mass, strength, power, and functional mobility as well as BMD. Keywords: Exercise training; Fracture prevention; Osteoporosis, Frailty. © 2023. The Author (s). Publication types.