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Histologic features of a normal fovea comprise a central area exclusively containing cones with elongated outer segments (OS) underlying a capillary-free zone and surrounded by separation of inner retinal layers. 1 The advent of optical coherence tomography (OCT), which allows noninvasive, cross-sectional imaging of the retina, made possible the...
By combining cellular scale adaptive optics imaging of macaque retina expressing the calcium indicator GCaMP6s with the presentation of high pre-cision, high spatial frequency binary white noise visual stimuli, we have revealed the functional topography of the foveola of a living primate.
4 de mai. de 2020 · Intraretinal haemorrhage appeared red and radiated outward from the foveal centre in a pattern consistent with localisation to the HFL. This haemorrhage extended mostly into the outer nuclear and outer plexiform layers with some hyperreflective material also within the inner nuclear layer.
1 de ago. de 2011 · Foveal OCT scans were assessed for outer retinal structure, outer nuclear layer thickness, and hypoplasia. AOSLO images were graded as quantifiable if a peak cone density could be measured and/or usable if the location of peak density could be identified and the parafoveal mosaic was quantifiable.
Significance. The sharpness of our eyesight hinges on a tiny retinal region known as the fovea. The fovea is pivotal for primate vision and is susceptible to diseases like age-related macular degeneration. We studied the fovea in the marmoset—a primate with ancient evolutionary ties.
1 de dez. de 2011 · The fovea is immature at birth. 7, 8 Histologic studies, originating with those of Mann in 1964, 9 have reported (1) persistence of IRL at the foveal center and absence of the normal foveal curvature in the fetal eye and (2) changes in the width and length of photoreceptor substructures over time.
In this review we consider how the vision restoration techniques currently being explored by the scientific community interact with the unique structure and physiology of the fovea and evaluate the prospects for restoring high quality foveal vision.
