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  1. 15 de jul. de 2016 · We investigated the patterns of metastasis from colon and rectal cancer to specific sites, depending on sex, age at diagnosis, histological subtype, stage, number of metastases, and whether the primary was situated in proximal or distal colon, or in the rectum.

  2. 17 de out. de 2022 · To develop recommendations for treatment of patients with metastatic colorectal cancer (mCRC). Methods. ASCO convened an Expert Panel to conduct a systematic review of relevant studies and develop recommendations for clinical practice. Results. Five systematic reviews and 10 randomized controlled trials met the systematic review inclusion criteria.

  3. 25 de out. de 2022 · This ESMO Clinical Practice Guideline provides key recommendations for managing metastatic colorectal cancer. •. It covers clinical and pathological diagnosis, staging and risk assessment, treatment and follow-up. •. Treatment algorithms for locoregional, advanced/metastatic and recurrent advanced colorectal cancer are provided. •.

  4. 28 de mai. de 2024 · Despite extensive research and improvements in understanding colorectal cancer (CRC), its metastatic form continues to pose a substantial challenge, primarily owing to limited therapeutic...

  5. 5 de jun. de 2022 · On the basis of the benefits seen in the context of metastatic disease, we hypothesized that single-agent programmed death 1 (PD-1) blockade alone might be beneficial in mismatch...