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21 de fev. de 2021 · Brain metastases (BM) from colorectal cancer (CRC) are rare. There is little available information regarding incidence, risk factors, prognostic factors, treatment, and overall survival (OS). In this systematic review we performed a research of the current literature and exposed an average incidence of 2.10%.
- Brain metastasis from colorectal cancer: Treatment, survival ...
To investigate the clinical characteristics, survival,...
- Brain metastasis from colorectal cancer: Treatment, survival ...
Results: We show that the incidence of BM in CRC patients ranges from 0.6 to 3.2 %. BM are a late stage phenomenon, and young age, rectal primary and lung metastases are associated with increased risk of developing BM.
- Troels Dreier Christensen, Karen-Lise Garm Spindler, Jesper Andreas Palshof, Dorte Lisbet Nielsen
- 2016
24 de dez. de 2020 · 1. Introduction. Colorectal cancers (CRCs) encompass two types of highly aggressive and common types of cancers, namely, colon and rectal. Globally, while colon cancer is the fourth most common malignancy, rectum cancer is the eight most common one [ 1 ].
- Ahmed Malki, Rasha Abu ElRuz, Ishita Gupta, Asma Allouch, Semir Vranic, Ala-Eddin Al Moustafa
- 10.3390/ijms22010130
- 2020
- Int J Mol Sci. 2021 Jan; 22(1): 130.
- Purpose
- Conclusion
- Parameters assessed
- Conclusion
- Data availability Not applicable.
- Declarations
Brain metastasis (BM) in colorectal cancer patients is rare and is associated with dismal outcomes. Our study aims to evaluate the incidence and predictors of BM in patients with colorectal cancer.
Our study supports the low incidence of brain metastasis in patients with colorectal cancer. A unique set of characteristics is identified to confer an increased risk of brain metastases. Keywords Brain metastasis · Predictors · Colorectal cancer · Incidence
We investigated variables from these patients include sex, age, race, ethnicity, population density, income, primary cancer site, CRC tumor grade, histological type, tumor size, regional lymph node involvement, and extracranial meta-static sites. Outcome measures were incidence and predic-tors of BM in colorectal cancer patients.
Colorectal cancer leading to brain metastasis is associated with high rates of mortality and poor prognosis. This study identified certain clinical characteristics that may predict the occurrence of BM, which may lead to earlier detection and diagnosis. We found the rate of BM to develop from CRC to be 0.30%. We recommend a supplemental study that ...
Code availability Surveillance, Epidemiology, and End Results Pro-gram (SEER) Data.
Competing interests The authors declare no competing interests.
- Elishia Thompson, Shoujit Banerjee, Sierra Thompson, Ryan Silva, Andrew Muse, Hina Arif-Tiwari, Aron...
- 2021
26 de nov. de 2012 · 1. Introduction. Colorectal carcinoma (CRC) is the third most commonly diagnosed cancer in males and the second most common in females worldwide [ 1 ]. The main causes of failure for treatments are local recurrence and distant metastases, especially when vital organs such as liver and lung are involved through hematogenous dissemination.
1 de dez. de 2012 · Article PDF Available Literature Review. Brain Metastasis of Colorectal Cancer: Microenvironment and Molecular Mechanism. December 2012. International Journal of Molecular...
