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  1. Claude de Lorraine, Duke of Guise (20 October 1496 – 12 April 1550) was a French aristocrat and general. He became the first Duke of Guise in 1528. He was a highly effective general for the French crown.

  2. In 1520, the Parlement of Paris awarded the countship of Guise to Claude of Lorraine, second son of René II of Lorraine (the grandson of René I of Naples) and heir to his French possessions. The countship was elevated to a dukedom in 1528.