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  1. Sir Augustus Frederick d'Este, KCH (13 January 1794 – 28 December 1848) was a relative of the British royal family and the earliest recorded person for whom a definite diagnosis of multiple sclerosis can be made.

  2. The Case of Augustus d'Este (1794-1848): The First Account of Disseminated Sclerosis: (Section of the History of Medicine) Proc R Soc Med. 1941 May;34 (7):381-4.

  3. Sir Augustus Frederick D’Esté (1794–1848) was an illegitimate royal child, a bachelor, an active member of the Aborigines Protection Society, and the earliest known person diagnosed with multiple sclerosis.

  4. Abstract. The personal diary of Sir Augustus d’Este ́, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  5. 17 de out. de 2009 · The personal diary of Sir Augustus d’Esté, born 1794 grandson of King George III of England, reveals a medical history strongly suggesting that Augustus suffered from multiple sclerosis (MS). It could well be the first record of a person having this disease.

    • Anne Marie Landtblom, Patrik Fazio, Sten Fredrikson, Enrico Granieri
    • 2010
  6. 31 de ago. de 2022 · Augustus D’Este, neto do rei George III, é conhecido como o primeiro paciente a ter Esclerose Múltipla (GARRARD & PETERS, 2012). Quando a neurologia se tornou um campo acadêmico?

  7. 4 de fev. de 2021 · It survives in the diaries (1822-48) and almanac of Sir Augustus D’Este, the Harrovian grandson of King George III. 1,2 In December 1822, when he was twenty-eight years old, Augustus suffered impaired vision in both eyes that recovered—probably bilateral optic neuritis.