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Há 1 dia · Over the past decade, proximal colon adenocarcinomas have been associated with worse overall and cancer-specific survival compared to distal cancers[1,2]. The explanation for these observations remains unclear. We hypothesized that proximal lesions may present with a more aggressive tumor biology leading to higher rates of lymph node (LN) metastases, and therefore, worse oncologic outcomes.
Há 4 dias · The team enrolled 112 participants with metastatic colorectal cancer who had previously undergone treatment with oxaliplatin and irinotecan-containing regimens in the Phase Ib/II trial. The...
Há 5 dias · A study led by UCLA Health Jonsson Comprehensive Cancer Center researchers found that using a combination of experimental immunotherapy drugs with chemotherapy significantly improves progression-free survival and overall survival for patients with metastatic colorectal cancer who have previously undergone standard chemotherapy ...
Há 4 dias · are contingent upon the site of metastasis. When deliberating the optimal therapeutic approach for a patient, thorough evaluation of significant risk factors such as the feasibility of complete resection, the presence of oligometastases, and the patient’s functional and physical condition is imperative. Recognizing the nuanced differences in RCC metastasis to distinct organs proves ...
Há 2 dias · Most deaths due to colon cancer are associated with metastatic disease. A gene that appears to contribute to the potential for metastatic disease, metastasis associated in colon cancer 1 (MACC1), has been isolated. It is a transcriptional factor that influences the expression of hepatocyte growth factor.
Há 3 dias · A 52-year-old man was referred to our team for assessment of a mass in the right atrium. The lesion, which initially appeared to be an extending thrombus in the inferior vena cava, had been seen on CT scan 6 months earlier as part of systematic surveillance for carcinoma of the colon (figure; appendix). He had been started on low molecular-weight heparin and re-commenced on both nivolumab and ...
Há 4 dias · Gastrointestinal Cancers: Colorectal Cancer. Type at least 3 characters. 633 articles. Filters. Original Research. Accepted on 24 May 2024. Survival Outcomes According to the Tumor Location and Prognostic factor in metastatic rectal cancer: a multicenter retrospective cohort study. Olcun Umit Unal. seval akay. huseyin salih semiz. murat keser.
