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Há 5 dias · Recurrent cervical cancer is a life-threatening disease, with limited treatment options available when disease progression occurs after first-line combination therapy. We conducted a phase 3, multi...
Há 21 horas · Jul 08, 2024, 3:26 pm. MONDAY, July 8, 2024 (HealthDay News) -- Second- or third-line treatment with tisotumab vedotin is efficacious for patients with recurrent cervical cancer, according to a study published in the July 4 issue of the New England Journal of Medicine. Ignace Vergote, M.D., Ph.D., from Universitaire Ziekenhuizen Leuven in ...
Há 21 horas · Cervical cancer (CC) is one of the most common gynecological tumors [].In 2020, there were 109,700 new cases and 59,000 deaths of CC in China [].Although vaccinations, radical surgery, and radio-chemotherapy have been widely used to prevent and treat CC, patients with advanced-stage, recurrence, and metastasis often lack effective treatment options, leading to poor overall prognosis.
Há 21 horas · Background: The sentinel lymph node is the first node that cancer cells reach when migrating from the primary site. However, oncological outcomes after sentinel lymph node biopsy (SNB) have not been reported for cervical cancer. In this study, oncological outcomes were compared between patients receiving SNB and pelvic lymphadenectomy (PLD) for early-stage cervical cancer. Methods: One hundred ...
Há 1 dia · Most of the studies included locally advanced cervical cancers, without restriction to squamous cell carcinomas but with a histological confirmation of the HPV status (24, 26–28, 33, 34). As our analyses were performed on serum residuals after SCC-A analyses, we excluded rare cervical tumors (adenocarcinomas and non-specified tumors) for which SCC-A assays are not routinely performed.
Há 4 dias · Cervical cancer (CC) is the fourth most common cancer among women worldwide. NLR Family CARD Domain Containing 5 (NLRC5) plays an important role in tumorigenesis. However, its effect and mechanism ...
Há 3 dias · Background Radioresistance is the leading cause of death in advanced cervical cancer (CC). Dysregulation of RNA modification has recently emerged as a regulatory mechanism in radiation and drug resistance. We aimed to explore the biological function and clinical significance of 5-methylcytosine (m5C) in cervical cancer radiosensitivity. Methods The abundance of RNA modification in radiotherapy ...
