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Há 3 dias · Colon cancer has a predilection for metastasizing to the liver—the venous drainage flows through the portal circulation where tumor cells are filtered by the hepatic parenchyma, and the entire cardiac output then passes through the pulmonary system. 32 Despite this biologic rationale, no randomized data have shown that resecting asymptomatic oligometastatic lesions in colon cancer improves ...
Há 1 dia · Since their 2018 edition, the National Comprehensive Cancer Network (NCCN) guidelines recommend either neoadjuvant single-agent chemoradiation with multi-agent adjuvant chemotherapy (CRT/MA ADJ) or total neoadjuvant chemoradiation (TNT) for the management of patients with the diagnosis of locally advanced rectal cancer (LARC). 1 However, several advantages have been associated with the TNT ...
Há 9 horas · Total neoadjuvant therapy (TNT) is a novel strategy for rectal cancer that administers both (chemo)radiotherapy and systemic chemotherapy before surgery. TNT is expected to improve treatment compliance, tumor regression, organ preservation, and oncologic outcomes. Multiple TNT regimens are currently available with various combinations of the treatments including induction or consolidation ...
Há 3 dias · NCCN, drawing on the expertise of faculty from its 21 member institutions, has developed and maintains clinical practice guidelines addressing colon and rectal cancers as part of its complete library of NCCN Clinical Practice Guidelines in Oncology™.
Há 2 dias · Right-sided colon cancer (RCC) and left-sided colon cancer (LCC) differ in features and outcomes because of variations in embryology, epidemiology, pathology, and prognosis. This study sought to ...
Há 3 dias · Article. Published: 28 May 2024. Clinical Studies. The road to tailored adjuvant chemotherapy for all four non-pancreatic periampullary cancers: An international multimethod cohort study. Bas A....
Há 2 dias · The NCCN Colon, Rectal, and Anal Cancers Guidelines provide sequential recommendations for the management of lower gastrointestinal malignancies.
