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Há 2 dias · Our analysis of changes in the cell therapy landscape over the past five years shows that the number of new trials peaked in 2021 and has since decreased by 3.9% in 2022 (led by a 10.5% reduction ...
Há 4 dias · OUTLOOK. 29 May 2024. Randomized trials of cancer drugs are for yesterday. Pitting new treatments against old, ineffective agents is neither ethical nor economical. By. Elaine Schattner. Over...
Há 5 dias · The evolution of these needs can be considered to be overlapping with the advancement of the concept of cancer-targeted therapy. Starting with methotrexate and 5-fluorouracil, advancing through tyrosin kinase inhibitors (TKI) and hormone therapy, current targeted therapy is oriented toward the use of multi-targeting drugs.
Há 3 dias · Pain is one of the most common symptoms in patients with cancer. Pain not only negatively affects the quality of life of patients with cancer, but it has also been associated with reduced survival. Pain management is therefore a critical component of cancer care. Prescription opioids remain the first-line approach for the management of moderate-to-severe pain associated with cancer. However ...
Há 5 dias · British Journal of Cancer - Nuclear factor-κB activation by transforming growth factor-β1 drives tumour microenvironment-mediated drug resistance in neuroblastoma
Há 4 dias · Our results established a clear association between cell uptake patterns and cell functions. Mechanomics can be analyzed with ML and possibly become a clinically relevant predictive tool for both cancer cell drug resistance and malignancy levels.
Há 3 dias · Manipulation of the gene networks underlying these cell states influenced the transition between them and may provide a rich source of potential targets for combinatorial cancer therapy. Stem cell states converge at early stages of carcinogenesis. Robust gene networks can be generated from many bulk-tissue samples.
