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Há 5 dias · Metastasis is a complex process involving cancer cells and tumor microenvironment. During cancer metastasis, cancer cells go through primary tumor, local invasion, spreading to circulation, and colonizing the distal secondary sites . Phenotypes of cancer cell dynamically alter during the process.
Há 1 dia · Objectives Lymph node metastasis (LNM) in colorectal cancer (CRC) patients is not only associated with the tumor’s local pathological characteristics but also with systemic factors. This study aims to assess the feasibility of using body composition and pathological features to predict LNM in early stage colorectal cancer (eCRC) patients. Methods A total of 192 patients with T1 CRC who ...
Há 4 dias · ABSTRACT. Colorectal cancer (CRC) is a complex and genetically heterogeneous disease presenting a specific metastatic pattern, with the liver being the most common site of metastasis. Around 20-25% of patients with CRC will develop exclusively hepatic metastatic disease throughout their disease history. With its specific ...
Há 4 dias · Colorectal cancer (CRC) is a prevalent gastrointestinal cancer posing significant clinical challenges. CRC management traditionally involves surgery, often coupled with chemotherapy. However, unresectable or metastatic CRC (mCRC) presents a complex challenge necessitating innovative treatment strategies.
Há 4 dias · Peritoneal metastases (PM) in colorectal cancer (CRC) is associated with a dismal prognosis. Identifying and exploiting new biomarkers, signatures, and molecular targets for personalised interventions in the treatment of PM in CRC is imperative. We conducted transcriptomic profiling using RNA-seq da …
Há 3 dias · Umbilical metastasis and colon cancer: A review on clinical features, current management and survival analysis June 2024 Surgery Open Digestive Advance 14(2–4):100145
Há 6 dias · Keywords: colorectal; cancer; emergency; analysis; outcome 1. Introduction Colorectal cancer (CRC) is a malignancy of the gastrointestinal tract that arises either from the colon or the rectum. Although colon cancer and rectal cancer can be defined as separate diseases, common biological and clinical features determine the study of colorectal
