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Há 2 dias · Despite extensive research and improvements in understanding colorectal cancer (CRC), its metastatic form continues to pose a substantial challenge, primarily owing to limited therapeutic options ...
Há 1 dia · Common sites of metastasis in B: liver 27%, lung 27%, locoregional lymph nodes 9%. In W pts: liver 24%, locoregional lymph nodes 24%, lung 10% and brain 5%. In H pts, 10 of 22(45%) were diagnosed without metastatic disease, though of the 10 who did, 2 had brain involvement. Mortality was highest in B pts at 55%, 33% for W, 20% for A and 18% for ...
Há 3 dias · The most common pathways in which metastases reaches the colon are via the lymphatics or vascular system, direct extension (i.e., invasion of contiguous colon wall), or peritoneal seeding. 6 Primary cancers that metastasize to the colon typically arise from the lung, breast, ovaries, prostate, kidneys, skin, stomach, or hepatobiliary system. 4 Metastatic lesions to the colon from an ...
Há 3 dias · Purpose Intracerebral metastases present a substantial risk of tumor-associated intracerebral hemorrhage (ICH). This study aimed to investigate the risk of hemorrhagic events in brain metastases (BM) from various primary tumor sites and evaluate the safety and outcomes of surgical tumor removal. Methods A retrospective, single-center review of medical records was conducted for patients who ...
Há 5 dias · However, cancer cells exhibit higher levels of aberrant hyperactivation of these components than healthy colonic mucosa cells. Overexpression of Notch pathways in cancers like colon cancer is linked to poor prognosis and therapeutic response. Notch signaling, which causes ALDH1A1 deacetylation, is associated with aggressive metastatic cancer.
Há 1 dia · The objective of this investigation was to analyse the correlation between the neutrophil-to-lymphocyte ratio (NLR) status in the immune microenvironment (IME) and the prognostic outcomes of patients who have undergone radical surgery for colorectal cancer (CRC).In light of the continued prevalence of CRC in China, this study utilised Kaplan–Meier and Cox regression analyses to assess the ...
Há 5 dias · Objective Perioperative Neurocognitive Disorders (PND) is a common neurological complication after radical colorectal cancer surgery, which increases adverse outcomes. So, our objective is to explore the influence of dexmedetomidine added to ropivacaine for transversus abdominis plane block (TAPB) on perioperative neurocognitive disorders, and to provide a new way to reduce the incidence of ...
