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Há 4 dias · Background Thyroid cancer (TC) is the most common endocrine malignancy. Nowadays, undifferentiated thyroid cancers (UTCs) are still lethal, mostly due to the insurgence of therapy resistance and disease relapse. These events are believed to be caused by a subpopulation of cancer cells with stem-like phenotype and specific tumor-initiating abilities, known as tumor-initiating cells (TICs). A ...
Há 1 dia · Background Diffuse sclerosing papillary thyroid carcinoma (DSPTC) is an aggressive histopathologic subtype of papillary thyroid carcinoma. Correlation between genotype and phenotype has not been comprehensively described. This study aimed to describe the genomic landscape of DSPTC comprehensively using next-generation sequencing (NGS), analyze the prognostic implications of different mutations ...
Há 5 dias · Results: Twenty-seven patients were included in this analysis. Patients with unresectable differentiated thyroid cancer (DTC) or poorly differentiated thyroid cancer (PDTC) received sorafenib (n = 6) or lenvatinib (n = 12), those with medullary thyroid cancer (MTC) were treated with vandetanib (n = 5) or selpercatinib (n = 1), and those with anaplastic thyroid cancer (ATC) harboring a BRAF ...
Há 2 dias · Medullary thyroid carcinoma (MTC), poorly differentiated tumours, and undifferentiated (anaplastic) thyroid carcinoma are rare in young patients . In several case series, pediatric and adolescent PTC (aged ≤ 20 years, referred to thereafter as CA-PTC) seems to have a different clinicopathological profile and outcome [ 4 ].
Há 3 dias · LBA6018 Background: Localizing medullary thyroid carcinoma (MTC) lesions is crucial for treatment decision, but the detection using the current imaging modalities is unsatisfied. Previously, we reported a 68Ga-labeled targeted covalent radiopharmaceutical fibroblast activation protein inhibitor (68Ga-TCR-FAPI), which demonstrated improved and sustained tumor targeting. This study aimed to head ...
Há 5 dias · Thyroid carcinoma can be divided into: anaplastic thyroid carcinoma (ATC), medullary thyroid carcinoma (MTC), and well-differentiated thyroid carcinoma [papillary (PTC) and follicular (FTC)] according to its histopathological features (Veschi et al. 2020).
Há 3 dias · An Insight into a Rare Case of Osteoclastic Variant of Anaplastic Thyroid Carcinoma Diagnosed by Fine Needle Aspiration Cytology (FNAC)View Book:- https://do...
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