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Há 2 dias · Advanced pancreatic ductal adenocarcinoma (PDAC) is notorious for its resistance to treatment, with limited benefit provided by chemotherapy, immunotherapy, and inhibitors of mutant KRAS, the ...
Há 1 dia · In cancer treatment, therapeutic strategies that integrate tumor-specific characteristics (i.e., precision oncology) are widely implemented to provide clinical benefits for cancer patients. Here, through in-depth integration of tumor transcriptome and patients’ prognoses across cancers, we investigated dysregulated and prognosis-associated genes and catalogued such important genes in a ...
Há 4 dias · Adenocarcinoma is the most common histopathological subtype of lung cancer. According to the international multidisciplinary classification by the International Association for the Study of Lung Cancer, American Thoracic Society, and European Respiratory Society, adenocarcinoma spectrum is defined as preinvasive adenocarcinoma, including atypical adenomatous hyperplasia, adenocarcinoma in situ ...
Há 3 dias · 551,000 (2018) [8] Colorectal cancer ( CRC ), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine ). [5] Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, abdominal pain and fatigue. [9]
Há 4 dias · Cancer prognosis remains a critical clinical challenge. Lipidomic analysis via mass spectrometry (MS) offers the potential for objective prognostic prediction, leveraging the distinct lipid profiles of cancer patient-derived specimens. This review aims to systematically summarize the application of MS-based lipidomic analysis in prognostic prediction for cancer patients. Our systematic review ...
Há 3 dias · É importante salientar que existem várias causas para sangramento nas fezes além do câncer de intestino. Hemorroidas, por exemplo, são causas comuns de sangramento anal (leia: Hemorroidas | Sintomas e tratamento ). No caso do câncer de cólon, quando há sangramento, o tumor costuma já estar bem avançado.
Há 2 dias · Aging and regeneration represent complex biological phenomena that have long captivated the scientific community. To fully comprehend these processes, it is essential to investigate molecular dynamics through a lens that encompasses both spatial and temporal dimensions. Conventional omics methodologies, such as genomics and transcriptomics, have been instrumental in identifying critical ...
