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Há 3 dias · Na imensa maioria dos casos, os pólipos são e permanecem sendo lesões benignas para o resto da vida. Existe, porém, um tipo de pólipo, chamado de adenomatoso, que pode se transformar em câncer. Cerca de 5% dos pólipos adenomatosos transformam-se em adenocarcinoma após cerca de 10 anos de existência.
Há 2 dias · Right-sided colon cancer (RCC) and left-sided colon cancer (LCC) differ in features and outcomes because of variations in embryology, epidemiology, pathology, and prognosis. This study sought to ...
Há 2 dias · Emergent advancements on the role of the intestinal microbiome for human health and disease necessitate well-defined intestinal cellular models to study and rapidly assess host, microbiome, and drug interactions. Differentiated Caco-2 cell line is commonly utilized as an epithelial model for drug permeability studies and has more recently been utilized for investigating host–microbiome ...
Há 3 dias · Colorectal cancer (CRC) is a prevalent gastrointestinal malignancy. Tumor-infiltrating lymphocyte (TIL) therapy, a form of adoptive cellular therapy (ACT), involves isolating T lymphocytes from tumor tissues, in vitro expansion, and reintroduction into the body to target and eliminate tumor cells. This article presents an overview of the development and application of TIL therapy in CRC, as ...
Há 3 dias · In cancer treatment, therapeutic strategies that integrate tumor-specific characteristics (i.e., precision oncology) are widely implemented to provide clinical benefits for cancer patients. Here, through in-depth integration of tumor transcriptome and patients’ prognoses across cancers, we investigated dysregulated and prognosis-associated genes and catalogued such important genes in a ...
Há 3 dias · Introduction. The term ‘intussusception’ refers to the invagination of one intestinal segment into the neighboring segment, causing bowel obstruction and potential intestinal ischemia [ 1 ]. Colonic intussusception that manifests in adulthood is extremely rare, occurring in less than 1 in 1300 abdominal surgeries.
Há 2 dias · The most common form of colon cancer is adenocarcinoma, constituting between 95% and 98% of all cases of colorectal cancer. Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes are more aggressive. Immunohistochemistry may be used in uncertain cases. Staging
