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Há 2 dias · Conclusions: DCIS progression is facilitated by interactions between stromal, immune, and epithelial cells, which lead to epigenetic and transcriptional changes. This results in the formation of stem-like cells that are characterized by their plasticity and invasive capacity. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I.
Há 2 dias · Purpose of Review Ductal carcinoma in situ (DCIS) accounts for roughly 25% of all new breast cancer diagnoses. Mortality from DCIS is low and has not significantly changed despite modern, aggressive care. This review will highlight the multiple strategies which are being proposed to de-escalate care, including foregoing sentinel lymph node biopsy (SLNB). Recent Findings Under 5% of patients ...
Há 3 dias · The vast majority of breast cancers are adenocarcinomas (99%). The most common types are 8: invasive carcinoma of no special type (ductal carcinoma not otherwise specified): 40-75%. ductal carcinoma in situ: 20-25%. invasive lobular carcinoma : 5-15%. Categories of benign epithelial neoplasms include: papillary lesions.
Há 1 dia · We leveraged paired tumor and normal sequencing data from 4918 primary and 611 metastatic breast cancer patients, as well as somatic genomic profiles from 341 patients with ductal carcinoma in situ (DCIS), and evaluated the relationship between germline-derived epitope burden (GEB) and subtype commitment, defined by the acquisition of focal oncogenic amplifications.
Há 2 dias · In a lot of cases, he said, an early-stage cancer called ductal carcinoma in situ “would have smoldered in the breast for a long time without women even knowing.”
Há 1 dia · I had my call from my surgeon regarding my surgery outcome. It is now a different diagnosis. It is PLCIS (Pleomorphic lobular carcinoma in suti) which is treated in a similar way to a higher grade DCIS. They thought they were existing 10mm, but it turned out to be 35mm - that was a shock too! I understand that LCIS is it’s oppo.
Há 2 dias · Breast cancer is the most common type of cancer of the female gender. A rare subtype of breast cancer is the invasive breast carcinoma (IBC) with neuroendocrine (NE) differentiation. Its incident is believed to be 0.1% to 5% of all breast cancers. We report a rare case of a 66-year old woman who presented with an isolated nodule of the left breast. The patient underwent modified radical ...
