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Cytomegalovirus is a double-stranded DNA virus that is a member of the herpesvirus family. Most people are CMV positive, with latency established in hematopoietic cells after primary infection. Immunosuppressed patients and kidney transplant recipients are particularly vulnerable. Seropositive recipients of a seropositive transplant are treated ...
2 de fev. de 2021 · Abstract. Human cytomegalovirus (HCMV) infection is common and affects between 40–100% of the worldwide population. However, the majority of cases are asymptomatic and when severe disease occurs, it is usually restricted to immunocompromised patients. Liver involvement by HCMV differs significantly, accordingly to the immune status of the host.
Since the signs and symptoms of CMV disease often overlap with other infectious processes and rejection, the diagnosis is made by integrating the clinical history, clinical presentation, and laboratory data. Because CMV produces lifelong latent infection, distinguishing active disease from latent infection and asymptomatic reactivation presents ...
17 de mai. de 2015 · Practice Essentials. Human Cytomegalovirus (CMV) is a member of the family Herpesviridae, also known as Human Herpesvirus 5 (HHV-5). It is the largest (220 nm in diameter) and most complex herpesvirus, with a 235,000 double-stranded DNA genome. CMV seroprevalence in immunocompetent adults varies from 40-100% globally.
Cytomegalovirus is the most common viral infection in organ transplant recipients that usually affects the brain, lungs, liver, and gastrointestinal tract. Renal involvement of Cytomegalovirus (CMV) is otherwise rare. We present six cases of biopsy-proven CMV renal infection. Five out of the six pat …
5 de out. de 2016 · Human cytomegalovirus (HCMV), a widely-spread β-herpesvirus, is a major cause of birth defects and opportunistic infections in HIV-1/AIDS patients. HCMV displays an intricate system-wide modulation of the human cell proteome. An impressive array of virus–host protein interactions occurs throughout the infection.
O CMV (vírus da herpes humana do tipo 5) é transmitido por sangue, líquidos corporais ou transplante de órgãos. A infecção pode ser adquirida por via transplacentária ou durante o nascimento. A prevalência aumenta com a idade; 50 a 90% dos adultos têm infecção por CMV (resultando em infecção latente por toda a vida) (1).
