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  1. Há 2 dias · Colorectal cancer is a leading cause of cancer-related mortality worldwide. Traditionally, colorectal cancer has been recognized as a disease caused by genetic mutations. However, recent studies have revealed the significant role of epigenetic alterations in the progression of colorectal cancer. Epithelial–mesenchymal transition, a critical step in cancer cell metastasis, has been found to ...

  2. Há 2 dias · METHODS We collected information on individuals who had a pathological diagnosis of colorectal cancer between 2000 and 2019 from the Surveillance, Epidemiology, and End Results (SEER) Database. We obtained data from patients who underwent pathological diagnosis of colorectal cancer and got comprehensive therapy at the hospital between January 1, 2010, and June 1, 2022.

  3. Há 2 dias · AbstractA number of neurotransmitters have been detected in tumor microenvironment and proved to modulate cancer oncogenesis and progression. We previously found that biosynthesis and secretion of neurotransmitter 5-hydroxytryptamine (5-HT) was elevated in colorectal cancer cells. In this study, we discovered that the HTR2B receptor of 5-HT was highly expressed in colorectal cancer tumor ...

  4. Há 1 dia · @article{Wehrle2024IntensiveLT, title={Intensive locoregional therapy before Liver Transplantation for colorectal cancer liver metastasis: A novel pre-transplant protocol.}, author={Chase J. Wehrle and Masato Fujiki and Andrea Schlegel and Melis Uysal and RN Anastasia Sobotka and Maureen Whitsett Linganna and Jamak Modaresi Esfeh and Suneel Kamath and Mazhar Khalil and Alejandro Pita and ...

  5. Há 23 horas · Colorectal cancer (CRC) is one of the most common malignant tumors, with the third highest incidence rate and the second highest mortality rate [].The 5-year survival rate of early-stage cancer can be as high as 90%, while the survival rate for patients with advanced colorectal cancer is less than 10% due to tumor metastasis, chemotherapy resistance and other complications [].

  6. Há 5 dias · Colorectal cancer (CRC), a pervasive and lethal malignancy of gastrointestinal cancer, imposes significant challenges due to the occurrence of distant metastasis in advanced stages. Understanding the intricate regulatory mechanisms driving CRC distant metastasis is of paramount importance.

  7. Há 1 dia · Intensive locoregional therapy before Liver Transplantation for colorectal cancer liver metastasis: A novel pre-transplant protocol.