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4 de mar. de 2022 · Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a high morbidity additionally, CRC patients may develop liver metastasis, which is the major cause of death.
20 de abr. de 2024 · Colorectal cancer is the third most common diagnosis and cause of cancer-related death in both sexes in the United States.[1] Worldwide, the condition remains the third most common malignancy but is second only to lung cancer in its mortality rate.[2] Incidence rates have been decreasing in Western countries, mostly due to the widespread use of colonoscopy screening. However, the condition's ...
2 de nov. de 2020 · The liver is one of the most common sites for cancer metastasis, which leads to secondary hepatic malignancies. Almost all solid tumors, such as melanoma, breast cancer, gastric cancer, colorectal ...
1 de jul. de 2017 · About 14 to 18% of patients with colorectal cancer present metastasis at the first medical consultation, and 10 to 25% at the time of the resection of the primary colorectal cancer. The incidence ...
19 de set. de 2019 · Metastasis is the major cause of death in patients with colorectal carcinoma (CRC). The most common sites of metastasis are the liver and the peritoneum. Peritoneal carcinomatosis is often considered the end stage of the disease after the tumor has spread to the liver. However, almost half of CRC patients with peritoneal carcinomatosis do not present with liver metastasis. This brings up the ...
7 de nov. de 2015 · Colorectal cancer (CRC) is a common malignancy worldwide. In CRC patients, metastases are the main cause of cancer-related mortality. In a group of metastatic CRC patients, the metastases are limited to a single site (solitary organ); the liver and lungs are the most commonly involved sites. When metastatic disease is limited to the liver and ...
alterations in cancer stem cells. J Exp Clin Cancer Res. 2018;37(1):118. 5. Qin X, et al. An oncogenic phenoscape of colonic stem cell polarization. Cell. 2023;186(25):5554–5568. 6. Caligiuri G, Tuveson DA. Activated fibroblasts in cancer: Perspectives and challenges. Cancer Cell. 2023;41(3):434–449. 7. He K, et al. Metastasis organotropism ...
