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  1. Há 2 dias · A novel combination comprising experimental immunotherapy drugs plus chemotherapy may improve survival outcomes in previously treated patients with metastatic colorectal cancer compared to the targeted therapy regorafenib alone. These findings will be presented by Wainberg et al at the 2024 ASCO Annual Meeting ( Abstract 3508 ). When colorectal ...

  2. Há 3 dias · Colorectal cancer ( CRC ), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine ). [5] Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, abdominal pain and fatigue. [9] Most colorectal cancers are due to old age ...

  3. Há 2 dias · Bailee Sliker: I start a new chapter as an Oncology Scientist/Medical Writer at NCCN / Bailee Sliker, cancer, Cancer Discovery, National Comprehensive Cancer

  4. Há 3 dias · The current healthcare system is unable to identify burdened and vulnerable families affected by cancer, partly due to a lack of knowledge of how cancer affects family health during treatment and survivorship. Recent reviews have documented a general lack of cancer studies including both the patien...

  5. Há 5 dias · The NCCN Guidelines for clinicians and patients now recommend the use of FES PET for ER+ positive disease under certain circumstances during the systemic staging workup of patients with recurrent or metastatic breast cancer. GE HealthCare’s Cerianna, available in the US, is the only FDA approved FES PET imaging agent.

  6. Há 3 dias · Appendiceal adenocarcinoma (AA) is an understudied and lethal malignancy with a profound lack of effective systemic treatments. Historically, management principles of appendiceal cancer have been derived from colon adenocarcinoma presumably due to its regional proximity although this generalization ignores clear differences between AA and colorectal cancer in terms of natural history ...

  7. Há 4 dias · Lynch syndrome (LS) is an autosomal-dominant hereditary disorder caused by genetic mutations in one of the four mismatch repair (MMR) genes MLH1, MSH2, MSH6, PMS2, or deletion of the EpCAM [epithelial cellular adhesion molecule] gene, which is necessary for MSH2 to work correctly. 1–5 Mismatch repair genes play a critical role in overseeing DNA mismatch repair and aid in the correct ...