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24 de abr. de 2020 · Nature Communications - Lymphatic metastases are closely associated with tumor relapse and reduced survival in colorectal cancer (CRC). Here, the authors analysed the primary tumours,...
- Chong Zhang, Lin Zhang, Tianlei Xu, Ruidong Xue, Liang Yu, Yuelu Zhu, Yunlong Wu, Qingqing Zhang, Do...
- 2020
Há 2 dias · Metastatic colorectal cancer ... The portal vein, which drains blood from the gastrointestinal tract, ... the spread of cancer to regional lymph nodes is associated with diminished DFS 15.
12 de mar. de 2021 · Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate. Thus, it is important to understand the mechanisms by which lymph node metastases progress and how they can be targeted to provide therapeutic benefits.
- Hengbo Zhou, Pin-Ji Lei, Timothy P Padera
- 10.3390/cells10030627
- 2021
- Cells. 2021 Mar; 10(3): 627.
15 de jul. de 2016 · Colorectal cancer (CRC) is the third most common cancer worldwide 1. Approximately 56% of patients with CRC die from their cancer 2. Development of metastasis is a concern for patients and...
- Matias Riihimäki, Matias Riihimäki, Akseli Hemminki, Jan Sundquist, Kari Hemminki, Kari Hemminki
- 2016
19 de set. de 2019 · Metastasis is the major cause of death in patients with colorectal carcinoma (CRC). The most common sites of metastasis are the liver and the peritoneum. Peritoneal carcinomatosis is often considered the end stage of the disease after the tumor has spread to the liver.
- E. Pretzsch, F. Bösch, J. Neumann, P. Ganschow, A. Bazhin, M. Guba, J. Werner, M. Angele
- 10.1155/2019/7407190
- 2019
- J Oncol. 2019; 2019: 7407190.
19 de jan. de 2024 · Tumor-draining lymph nodes (TDLNs) are located along the lymphatic drainage pathway of primary tumors and are the primary sites at which anti-tumor lymphocytes are activated by tumor-specific antigens.1 TDLNs contain tumor-specific T cells and are a good source of T cells for colorectal cancer (CRC) immunotherapy.
The invasion of lymphatic vessels by colorectal cancer (CRC) and its subsequent spread to draining lymph nodes is a key determinant of prognosis in this common and frequently fatal malignancy.
