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  1. 22 de ago. de 2023 · Hypercoagulability or thrombophilia is the increased tendency of blood to thrombose. A normal and healthy response to bleeding for maintaining hemostasis involves the formation of a stable clot, and the process is called coagulation.

    • 2023/08/22
  2. 18 de mai. de 2023 · The most common presentations of venous thromboembolism (VTE) are deep vein thrombosis of the lower extremity and pulmonary embolism. Risk factors for VTE, either acquired or hereditary, can be identified in the majority of patients who present with VTE [ 1-3 ].

  3. 25 de mai. de 2023 · Patients who have an identifiable thrombophilic risk factor should be advised to have blood relatives tested, as this information would be important for their physicians, in deciding whether to...

  4. 28 de nov. de 2023 · The calculations based on a total of 15 studies showed that a strategy of thrombophilia testing followed by indefinite anticoagulant treatment for patients with thrombophilia and stopping anticoagulant treatment for patients without thrombophilia would lead to 3 per 1000 fewer major bleeds in patients at low risk of bleeding (ranging ...

    • Middeldorp, Saskia
  5. 25 de jun. de 2014 · Hypercoagulability, also known as thrombophilia, describes a group of hereditary and acquired conditions which confer a propensity to develop thrombi in the veins, arteries, or both. Based on current knowledge, antiphospholipid syndrome is the most prevalent hypercoagulable state, followed by factor V Leiden (FVL) mutation ...

    • Megan O. Nakashima, Heesun J. Rogers
    • 10.5045/br.2014.49.2.85
    • 2014
    • Blood Res. 2014 Jun; 49(2): 85-94.
  6. 3 de dez. de 2015 · Our study shows that those patients with PMH or FH of VTE were more likely to have thrombophilia studies. There is no consensus opinion as to whether to perform thrombophilia screenings in acute care settings.

  7. 21 de set. de 2017 · Summary of Recommendations Regarding Testing for Thrombophilia. The controversy surrounding testing stems from the demonstrated lack of effect of thrombophilia status on VTE outcomes,...