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4 de ago. de 2022 · Molecular characterization of colorectal cancer related peritoneal metastatic disease | Nature Communications. Article. Open access. Published: 04 August 2022. Molecular...
19 de abr. de 2022 · View article impact. Share on. ORIGINAL RESEARCH article. Front. Oncol., 19 April 2022. Sec. Gastrointestinal Cancers: Colorectal Cancer. Volume 12 - 2022 | https://doi.org/10.3389/fonc.2022.813253. Comprehensive Molecular Profiling of Colorectal Cancer With Situs Inversus Totalis by Next-Generation Sequencing.
2 de jun. de 2022 · 3535Background: Approximately 20% of colorectal cancer (CRC) has an activating mutation in the PIK3CA oncogene. PIK3CA codes for the catalytic subunit of phosphoinos... Molecular characteristics of advanced colorectal cancer and multi-hit PIK3CA mutations. | Journal of Clinical Oncology
24 de mai. de 2023 · Details. Online-only access $25.00. Details. PDF download and online access $59.00. Details. Check out. Abstract. Tumor profiling and targeted therapy revolutionized the treatment strategies of metastatic colorectal cancer (mCRC) in the last decade.
10 de nov. de 2022 · We investigated the molecular features of 133 colorectal cancer cases by comprehensive genomic profiling of 425 cancer-related genes. Consistent with previous research ( 17 ), APC (77.4%), TP53 (72.9%), and KRAS (53.4%) represented the most frequently mutated genes in our cohort.
- 10.3389/fonc.2022.1000146
- 2022
- Front Oncol. 2022; 12: 1000146.
Coloncancer(CC)isthethirdleadingcauseofcancer-related death inadultpatientsintheUS.Anestimated106,180newCC cases and 52,580 deathsareexpected in2022. Althoughnew 1. 2 , treatments have 3 improved outcomes, thefiveyearrelativesurvival remains pooratonly64.7%. 2 Theoddsareworseforpatientswith.
19 de jan. de 2022 · Background: Molecular characterisation of colorectal cancer (CRC) has demonstrated the regulatory role of epigenetic alterations, such as DNA methylation, in CRC tumorigenesis (1). Robust molecular profiling of CRC has the potential to provide critical diagnostic and prognostic information.
