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30 de mar. de 2020 · The reversed cone-like molecular shape of CD9 generates membrane curvature in the crystalline lipid layers, which explains the CD9 localization in regions with high membrane curvature and...
- Rie Umeda, Yuhkoh Satouh, Yuhkoh Satouh, Mizuki Takemoto, Yoshiko Nakada-Nakura, Kehong Liu, Takeshi...
- 2020
28 de abr. de 2020 · CD9, a 24 kDa tetraspanin membrane protein, is known to regulate cell adhesion and migration, cancer progression and metastasis, immune and allergic responses, and viral infection. CD9 is...
- Jung Hee Cho, Jung Hee Cho, Eok-Cheon Kim, Youlim Son, Da-Woon Lee, Yong Seop Park, Joon Hyuk Choi, ...
- 2020
CD9 is located in the microvillar membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli. [23] CD9 can also modulate cell adhesion [24] and migration. [25] [26] This function makes CD9 of interest when studying cancer and cancer metastasis.
9 de out. de 2018 · CD9 is a tetraspanin family member. Tetraspanin proteins are ubiquitously expressed and consist of 4 transmembrane domains, an intracellular terminus and 2 extracellular loops ( 1 ). Tetraspanins function as organizers of the cell surface by recruiting specific partner proteins into tetraspanin-enriched microdomains (TEMs) ( 2 ).
- Carole Brosseau, Luc Colas, Antoine Magnan, Sophie Brouard
- 10.3389/fimmu.2018.02316
- 2018
- Front Immunol. 2018; 9: 2316.
6 de nov. de 2018 · Abstract. Tetraspanin CD9 is essential for sperm–egg fusion and also contributes to uterine repair through microexosome formation. Microexosomes share CD9 with exosomes and are released from...
- Maki Iwai, Toshio Hamatani, Akihiro Nakamura, Akihiro Nakamura, Natsuko Kawano, Seiya Kanai, Woojin ...
- 2019
29 de abr. de 2018 · Front. Immunol., 29 April 2018. Sec. Antigen Presenting Cell Biology. Volume 9 - 2018 | https://doi.org/10.3389/fimmu.2018.00863. This article is part of the Research Topic Functional Relevance of Tetraspanins in the Immune System View all 13 articles. Tetraspanin CD9: A Key Regulator of Cell Adhesion in the Immune System.
CD9 is the main member of the tetraspanin group present on platelets.165 It is a 24-kDa protein with a single N-glycosylation site and four transmembrane domains.
