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29 de abr. de 2018 · In this context, CD9 has been shown to play an important role in the regulation of ALCAM-mediated cell adhesion and T cell activation. On leukocytes, CD9 acts as a scaffold in ALCAM-containing TEMs, engaging in direct lateral interactions through its LEL domain with the extracellular region of ALCAM, therefore, upregulating its ...
- CD9 Tetraspanin: A New Pathway for the Regulation of ...
CD9 belongs to the tetraspanin superfamily. Depending on the...
- CD9 Tetraspanin: A New Pathway for the Regulation of ...
28 de abr. de 2020 · CD9, a 24 kDa tetraspanin membrane protein, is known to regulate cell adhesion and migration, cancer progression and metastasis, immune and allergic responses, and viral infection. CD9 is...
- Jung Hee Cho, Jung Hee Cho, Eok-Cheon Kim, Youlim Son, Da-Woon Lee, Yong Seop Park, Joon Hyuk Choi, ...
- 2020
30 de mar. de 2020 · Nature Communications - Tetraspanins play critical roles in various physiological processes, ranging from cell adhesion to virus infection. Here authors report the crystal structure of CD9...
- Rie Umeda, Yuhkoh Satouh, Yuhkoh Satouh, Mizuki Takemoto, Yoshiko Nakada-Nakura, Kehong Liu, Takeshi...
- 2020
30 de abr. de 2018 · Through these associations, CD9 influences many cellular activities in the different subtypes of leukocytes and in endothelial cells, including intracellular signaling, proliferation, activation, survival, migration, invasion, adhesion, and diapedesis.
- Raquel Reyes, Beatriz Cardeñes, Yesenia Machado-Pineda, Carlos Cabañas, Carlos Cabañas
- 2018
24 de jul. de 2019 · CD9-depleted PECs displayed a strong delay in adhesion to plastic (Fig. 4a) that was associated with reduced cell spreading (3012 ± 135.7 vs. 1649 ± 70.7 µm 2 for scramble and Cd9 shRNA...
Abstract. CD9, a 24 kDa tetraspanin membrane protein, is known to regulate cell adhesion and migration, cancer progression and metastasis, immune and allergic responses, and viral infection. CD9 is upregulated in senescent endothelial cells, neointima hyperplasia, and atherosclerotic plaques.
