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12 de mar. de 2020 · Cervical adenocarcinoma in situ is a unique diagnosis whose management needs to be differentiated from the management of the more prevalent squamous cell dysplasia.
- Deanna Teoh, Fernanda Musa, Ritu Salani, Warner Huh, Edward Jimenez
- 10.1097/AOG.0000000000003761
- 2020
- Obstet Gynecol. 2020 Apr; 135(4): 869-878.
16 de ago. de 2022 · AIS is a premalignant precursor to cervical adenocarcinoma that can be prevented by appropriate management. Learn about the diagnosis, epidemiology, and treatment of AIS from this comprehensive article.
31 de jan. de 2020 · Essential features. Neoplastic glandular precursor for invasive endocervical adenocarcinoma. Variable histologic features based on adenocarcinoma in situ type. Most adenocarcinoma in situ types are associated with high risk human papillomavirus (HPV)
- Conization
- Fertility-Sparing Treatment
- AIS Diagnosed in Pregnancy
- Hysterectomy
- GeneratedCaptionsTabForHeroSec
If AIS is diagnosed by CGB or ECC an excisional biopsy is required in all women before any subsequent management decisions [21•, 27]. With respect to the type of conization, different modalities are acceptable. Some institutions would rather perform loop electrosurgical excision procedures (LEEP), whereas others opt for cold knife conization (CKC) ...
For selected women who wish to preserve fertility, conservative management, i.e., conization followed by surveillance, might be an acceptable option [21•]. Of note, it is crucial that these women are counseled adequately and informed of the risk for recurrent AIS and adenocarcinoma. Where conservative management is to be undertaken, several criteri...
According to ASCCP guidelines, pregnant women with any type of abnormal cervical cytology should be referred for colposcopy and CGB [21•]. Once invasive cancer is excluded, conservative management of squamous lesions in pregnancy is considered safe. Pregnant women are rarely diagnosed with AIS. Diagnostic conization is recommended during pregnancy ...
Hysterectomy remains the preferred standard treatment for women diagnosed with AIS [21•]. AIS is frequently present in multifocal areas and as well as skip lesions that are not contiguous and can be several millimeters away from areas free of AIS. Therefore, negative margins on a diagnostic excisional specimen do not necessarily mean that the lesio...
A review of the pathogenesis, incidence, prevention, diagnosis and treatment of AIS, a precursor of invasive adenocarcinoma of the cervix. Learn about the role of HPV vaccination, cytology, colposcopy, conization and hysterectomy in AIS management.
- Stephan Polterauer, Alexander Reinthaller, Reinhard Horvat, Elmar Joura, Christoph Grimm
- 2013
This publication represents an extensive literature review with the goal of providing guidelines for the evaluation and management of cervical adenocarcinoma in situ (AIS).
- Deanna Teoh, Fernanda Musa, Ritu Salani, Warner Huh, Edward Jimenez
- 2020
The most significant cause of cervical cancer is persistent papillomavirus infection. HPV is detected in 99% of cervical tumours, particularly the oncogenic subtypes such as HPV 16 and 18.
17 de mar. de 2021 · Learn how to diagnose and treat adenocarcinoma in situ (AIS), a HPV-associated precancerous lesion of the endocervix. Find out the steps for excisional biopsy, hysterectomy, and surveillance for patients with or without fertility desire.
