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  1. 1 de mar. de 2006 · Hopeful monsters are organisms with a profound mutant phenotype that have the potential to establish a new evolutionary lineage. The Synthetic Theory of evolutionary biology has rejected the evolutionary relevance of hopeful monsters, but could not fully explain the mechanism and mode of macroevolution.

    • Günter Theißen
    • 2006
  2. His ideas about macromutations became known as the "hopeful monster" hypothesis, a type of saltational evolution, and attracted widespread ridicule. According to Goldschmidt, "biologists seem inclined to think that because they have not themselves seen a 'large' mutation, such a thing cannot be possible.

  3. 1 de jan. de 2003 · Hopeful monsters to homeotic mutation. Goldschmidt spent the final years of his life researching HOMEOTIC MUTANTS in Drosophila. He saw homeotic mutants such as ARISTAPEDIA as hopeful

    • Michael R. Dietrich
    • 2003
  4. In addition, we define the favored precursors, or "hopeful monsters," for the origin of de novo genes and present a discussion of the functional significance of these young genes in brain development and tumorigenesis in humans. This article is categorized under: RNA Evolution and Genomics > RNA and Ribonucleoprotein Evolution.

  5. 1 de ago. de 2009 · Geneticist Richard Goldschmidt hypothesized that macroevolution proceeded by the succeed of "hopeful monsters" in 1933, which was a kind of mechanism that was different from Darwinian...

  6. 17 de fev. de 2010 · Thanks to the way regulatory DNA sequences are organized — as independent modules — evolution had managed a surgical strike on Pitx1, resulting in a beast hopeful and not so monstrous after all.

  7. 16 de fev. de 2022 · “The animal won’t have any chance of surviving. Biologist Richard Goldschmidt called them ‘hopeless monsters.’” But once in a very long while, one of these radical changes might provide a beneficial trait in a particular environment, creating a “hopeful monster.”