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28 de mai. de 2024 · Download PDF. Review ... the main cause of death in colorectal cancer (CRC), its molecular basis remains ... and treatment of ERBB2-positive metastatic colorectal cancer. JAMA Oncol. 8, 760 (2022).
29 de mai. de 2024 · To explore the status of Th1l in colorectal cancer, we first investigated the amplification of the Th1l gene in stool samples from patients with CRC (n = 97) or IBD (n = 79) and healthy controls (n = 74).
13 de mai. de 2024 · The molecular categorization of colon cancer patients remains elusive. Gene set enrichment analysis (GSEA), which investigates the dysregulated genes among tumor and normal samples, has...
27 de mai. de 2024 · Background Genetic factors and microbial imbalances play crucial roles in colorectal cancers (CRCs), yet the impact of infections on cancer initiation remains poorly understood. While bioinformatic approaches offer valuable insights, the rising incidence of CRCs creates a pressing need to precisely identify early CRC events. We constructed a network model to identify continuum states during ...
Há 1 dia · Colorectal cancer (CRC) is among the most common malignant tumors in humans and is the leading cause of cancer-related deaths worldwide after lung cancer. 1, 2 Nearly 90% of CRC-related deaths are caused by distant metastasis of cancer cells, primarily liver metastasis. 3 Although clinical diagnosis and treatment have improved and prolonged patient survival, the survival prognosis of patients ...
13 de mai. de 2024 · We assessed the expression levels of CASC19 and LINC00460 genes in a pool of colon cell lines: DLD-1, COLO-205, HCT116, and LoVo as colon cancer models and CCD841 as a normal epithelial cell...
9 de mai. de 2024 · Methods. Single-cell RNA sequencing (scRNA-seq) data of MSI-H CRC patients were obtained from the Gene Expression Omnibus (GEO) database. By utilizing the copy number variation (CNV) score, a malignant cell subpopulation was identified at the single-cell level.
