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29 de mai. de 2024 · GIST histology, particularly with local invasion, significantly raises mortality. Further research can unravel histopathology and staging's impact on overall and cancer-specific mortality, aiding targeted therapy.
Há 5 dias · Subjects with unfavourable histology experienced biochemical recurrence at a rate 20.8 times that of subjects with favourable histology (HR = 20.8; 95% CI = 10.2–42.4). Two multivariable Cox proportional hazards models were fitted for biochemical recurrence, one using variables included in the MSKCC Post-Radical Prostatectomy Nomogram and one expanded model in which unfavourable histology ...
1 de jun. de 2024 · A multimodal deep learning prognostic model based on histopathology outperforms current gold standards for identifying patients with endometrial cancer with different outcomes, in multiple ...
Há 3 dias · Using high-resolution ex vivo MRI and serial histology, Ravikumar et al. characterise 3D tau spread across histologically defined medial temporal lobe subregions thus providing a postmortem ...
27 de mai. de 2024 · The Journal of Molecular Histology publishes 6 times a year full-length original research papers, review articles, short communications and letters to the ...
Há 5 dias · The study sets new performance benchmarks and explores the intersection of histology and proteomics, highlighting phenotypes related to treatment response pathways, including homologous recombination, DNA damage response, nucleotide synthesis, apoptosis, and ER stress.
Há 2 dias · Current clustering analysis of spatial transcriptomics data primarily relies on molecular information and fails to fully exploit the morphological features present in histology images, leading to compromised accuracy and interpretability. To overcome these limitations, we have developed a multi-stage statistical method called iIMPACT. It identifies and defines histology-based spatial domains ...
